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| Content Provider | Springer Nature Link |
|---|---|
| Author | Bonate, P. L. Strougo, A. Desai, A. Roy, M. Yassen, A. Walt, J. S. Kaibara, A. Tannenbaum, S. |
| Copyright Year | 2012 |
| Abstract | Quality population modeling and simulation analyses and reports are something every modeler desires. However, little attention in the literature has been paid to what constitutes quality regarding population analyses. Very rarely do published manuscripts contain any statement about quality assurance of the modeling results contained therein. The purpose of this manuscript is to present guidelines for the quality assurance of population analyses, particularly with regards to the use of NONMEM from an industrial perspective. Quality guidelines are developed for the NONMEM installation itself, NONMEM data sets, control streams, output listings, output data files and resultant post-processing, reporting of results, and the review processes. These guidelines were developed to be thorough yet practical, though are not meant to be completely comprehensive. It is our desire to ensure that what is reported accurately reflects the collected data, the modeling process, and model outputs for a modeling project. |
| Starting Page | 749 |
| Ending Page | 758 |
| Page Count | 10 |
| File Format | |
| ISSN | 12341234 |
| Journal | The AAPS Journal |
| Volume Number | 14 |
| Issue Number | 4 |
| e-ISSN | 15507416 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2012-07-24 |
| Publisher Institution | American Association of Pharmaceutical Scientists |
| Publisher Place | Boston |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | modeling NONMEM quality assurance Biotechnology Pharmacy Biochemistry Pharmacology/Toxicology |
| Content Type | Text |
| Resource Type | Article |
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