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| Content Provider | Springer Nature Link |
|---|---|
| Author | Regmi, Hem Nesamony, Jerry Devabhaktuni, Vijay |
| Copyright Year | 2017 |
| Abstract | The purpose of this project was to design a computational decision support system (DSS) for compounded sterile preparations (CSP).Error-free compounding is dependent on the proper selection of components and adherence to procedure during compounding. A material selection system (MSS) based on a graphical user interface (GUI), coupled with a barcode scanner and back-end database, was developed and tested for proper selection of items involving three different medication orders (MO). A video processing system (VPS) was implemented in MATLAB that evaluated live video feed from the compounding hood to monitor the compounding procedure when compounding the MO’s. Surf detection was used to detect and locate compounding items placed in the hood. Various algorithms were developed and tested to enhance the accuracy and robustness of the VPS.The MSS was tested for all items used in compounding the MO’s, and it performed error-free. The VPS evolved to VPS.03 from VPS.01 and VPS.02. The greatest accuracy and ability for real-time realization were seen in VPS.03. All deliberate mistakes made when compounding the tested medication orders were captured by VPS.03.The new computational decision support system facilitated error-free selection of components and was able to monitor and evaluate the compounding process in real time. The platform may be used in CSP compounding rooms, to audit techniques and procedures, and in training or educational settings. |
| Starting Page | 124 |
| Ending Page | 141 |
| Page Count | 18 |
| File Format | |
| ISSN | 18725120 |
| Journal | Journal of Pharmaceutical Innovation |
| Volume Number | 12 |
| Issue Number | 2 |
| e-ISSN | 19398042 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2017-02-21 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Decision support system Compounded sterile preparation Graphical user interface MATLAB Material selection system (MSS) Video processor system (VPS) Medication order (MO) Pharmacology/Toxicology Industrial and Production Engineering Biotechnology Biochemical Engineering |
| Content Type | Text |
| Resource Type | Article |
| Subject | Drug Discovery Pharmaceutical Science |
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