NDLI: In vitro effects on biofilm viability and antibacterial and antiadherent activities of silymarin

Content Provider	Springer Nature Link
Author	Evren, Ebru Yurtcu, Erkan
Copyright Year	2015
Abstract	Limited treatment options in infectious diseases caused by resistant microorganisms created the need to search new approaches. Several herbal extracts are studied for their enormous therapeutic potential. Silymarin extract, from Silybum marianum (milk thistle), is an old and a new remedy for this goal. The purpose of this study is to evaluate the antibacterial and antiadherent effects of silymarin besides biofilm viability activity on standard bacterial strains. Minimal inhibitory concentration (MIC), minimal bactericidal concentration (MBC), antiadherent/antibiofilm activity, and effects on biofilm viability of silymarin were evaluated against standard bacterial strains. MIC values were observed between 60 and >241 μg/mL (0.25–>1 mmol/L). Gram-positive bacteria were inhibited at concentrations between 60 and 120 μg/mL. Gram-negative bacteria were not inhibited by the silymarin concentrations included in this study. MBC values for Gram-positive bacteria were greater than 241 μg/mL. Adherence/biofilm formations were decreased to 15 μg/mL silymarin concentration when compared with silymarin-untreated group. Silymarin reduced the biofilm viabilities to 13 and 46 % at 1 and 0.5 mmol/L concentrations, respectively. We demonstrated that silymarin shows antibacterial and antiadherent/antibiofilm activity against certain standard bacterial strains which may be beneficial when used as a dietary supplement or a drug.
Starting Page	351
Ending Page	356
Page Count	6
File Format	PDF
ISSN	00155632
Journal	Folia Microbiologica
Volume Number	60
Issue Number	4
e-ISSN	18749356
Language	English
Publisher	Springer Netherlands
Publisher Date	2015-05-04
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Life Sciences Microbiology Applied Microbiology Immunology Environmental Engineering/Biotechnology
Content Type	Text
Resource Type	Article
Subject	Medicine Microbiology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Effects of ginkgoneolic acid on the growth, acidogenicity, adherence, and biofilm of Streptococcus mutans in vitro

Antibacterial and mutagenic activities of new isothiocyanate derivatives

Antibacterial effects of trisubstituted quinazoline derivatives

Antibacterial effects of some 1-substituted 1,2,4-triazoles

In Vitro antibacterial effects of antilipopolysaccharide DNA aptamer-C1qrs complexes

Immunomodulatory effects ofBacillus firmus on mouse peritoneal cellsin Vitro

Antibacterial activity of N-benzylsalicylthioamides

Effect of environmental factors on biofilm formation by clinicalStenotrophomonas maltophilia isolates

Experimental biofilm and its application in malathion degradation

In vitro effects on biofilm viability and antibacterial and antiadherent activities of silymarin

Similar Documents

Effects of ginkgoneolic acid on the growth, acidogenicity, adherence, and biofilm of Streptococcus mutans in vitro

Antibacterial and mutagenic activities of new isothiocyanate derivatives

Antibacterial effects of trisubstituted quinazoline derivatives

Antibacterial effects of some 1-substituted 1,2,4-triazoles

In Vitro antibacterial effects of antilipopolysaccharide DNA aptamer-C1qrs complexes

Immunomodulatory effects ofBacillus firmus on mouse peritoneal cellsin Vitro

Antibacterial activity of N-benzylsalicylthioamides

Effect of environmental factors on biofilm formation by clinicalStenotrophomonas maltophilia isolates

Experimental biofilm and its application in malathion degradation

In vitro effects on biofilm viability and antibacterial and antiadherent activities of silymarin