NDLI: Electrospun grape seed polyphenols/gelatin composite fibers contained silver nanoparticles as biomaterials

Content Provider	Springer Nature Link
Author	Han, Xiaotong Xing, Zuge Si, Shaoxiong Yao, Yongyi Zhang, Qiyi
Copyright Year	2014
Abstract	GSP/gelatin composite nanofiber membranes containing silver nanoparticles were successfully fabricated as a novel biomaterial by electrospinning. The silver nanoparticles (AgNPs) were synthesized with the grape seed polyphenols (GSP) as reducing agent in aqueous solution of gelatin, and then the GSP/gelatin/AgNPs mixed solution was electrospun into nanofibers at 55 °C. The scanning electron microscopy (SEM) confirmed that the composite fibers were uniform and the average fiber diameter ranged between 150 nm and 230 nm with an increase in applied potentials from 14 kV to 22 kV. And the transmission electron microscopy (TEM) showed that silver nanoparticles distributed individually in the fibers with the average particle size of about 11 nm. Furthermore, the ultraviolet visible spectrophotometer (UV-vis spectroscopy) test demonstrated that all of Ag$^{+}$ converted to Ag$^{0}$ when the concentration of gelatin was 24 wt% and the mass ratio of GSP to AgNO$_{3}$ was about 5:2. The antibacterial activities of the fiber membranes against E.coli and S.aureus were measured via a shake flank test and demonstrated good performance after the importation of silver nanopaticles. Cytotoxicity testing also revealed that fiber membranes contained silver nanoparticles had no cyto-toxic. All the results indicated that the GSP was effective for the formation and stabilization of silver nanoparticles in composite nanofibers mats which had the potential for applications in antimicrobial tissue engineering and wound dressing.
Starting Page	2572
Ending Page	2580
Page Count	9
File Format	PDF
ISSN	12299197
Journal	Fibers and Polymers
Volume Number	15
Issue Number	12
e-ISSN	18750052
Language	English
Publisher	The Korean Fiber Society
Publisher Date	2015-01-04
Publisher Place	Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Nanofibers Silver nanoparticles Grape seed polyphenols Gelatin Electrospun Antibacterial Polymer Sciences
Content Type	Text
Resource Type	Article
Subject	Chemistry Chemical Engineering Polymers and Plastics

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