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| Content Provider | Springer Nature Link |
|---|---|
| Author | Festa, Michela Ruffo, Alfredo |
| Copyright Year | 2000 |
| Abstract | It has been investigated whether oxalomalate (OMA) the competitive inhibitor of cytosolic aconitase might extend its effect also on IRP-1, an iron regulatory protein, probably present in a commercial preparation of purified aconitase. The results showed that IRP-1 is contained in the purified preparation and was strongly inhibited during the incubation with OMA. The effect produced by OMA on the bi-functional protein IRP-1/aconitase was discussed.È stato indagato l’effetto dell’OMA, ben noto inibitore competitivo della forma citosolica di aconitasi, sulla eventuale presenza di IRP-1 in una preparazione commerciale di aconitasi purificata. I risultati hanno dimostrato che IRP-1 è presente nella preparazione purificata e viene fortemente inibita nel corso di una breve incubazione con OMA 5 mM, a temperatura ambiente. Viene messa in evidenza l’inibizione prodotta da OMA su entrambe le forme della proteina bifunzionale IRP-1/Aconitasi. |
| Starting Page | 111 |
| Ending Page | 114 |
| Page Count | 4 |
| File Format | |
| ISSN | 11206349 |
| Journal | Rendiconti Lincei |
| Volume Number | 11 |
| Issue Number | 2 |
| e-ISSN | 17200776 |
| Language | Lithuanian |
| Publisher | Springer-Verlag |
| Publisher Date | 2000-01-01 |
| Publisher Place | Milan |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Oxalomalate Iron regulatory protein Aconitase Environment Geosciences Life Sciences Biomedicine general History of Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Earth and Planetary Sciences Environmental Science Agricultural and Biological Sciences |
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