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| Content Provider | Springer Nature Link |
|---|---|
| Author | Zhang, Zhi xiong Sun, Jun wei Yuan, Jing qi |
| Copyright Year | 2015 |
| Abstract | In the two-step vitamin C fermentation process, its precursor 2-keto-L-gulonic acid was synthesized from L-sorbose by mixed culture of Gluconobacter oxydans and Bacillus megaterium. The interaction between Gluconobacter oxydans and Bacillus megaterium remains unclear and it is a challenge to mathematically model the mixed growth of these two strains. The Monod-type equations were previously proposed to describe the coupled growth of Gluconobacter oxydans and Bacillus megaterium. However, in this study, we modeled the interaction of these two strains in a macroscopic view by introducing the population theory. Taking account of the fact that the density or concentration of Gluconobacter oxydans or Bacillus megaterium was hardly to measure accurately in the mixed culture broth, the data of concentrations of the substrate and product were used to indirectly investigate the relation between these two strains. Three batch experiments were used to validate our model. And according to the values of identified parameters, the type of interaction between Gluconobacter oxydans and Bacillus megaterium was concluded to be predation, where Gluconobacter oxydans was predator, and Bacillus megaterium was prey. |
| Starting Page | 281 |
| Ending Page | 285 |
| Page Count | 5 |
| File Format | |
| ISSN | 10071172 |
| Journal | Journal of Shanghai Jiaotong University (Science) |
| Volume Number | 20 |
| Issue Number | 3 |
| e-ISSN | 19958188 |
| Language | English |
| Publisher | Shanghai Jiaotong University Press |
| Publisher Date | 2015-10-23 |
| Publisher Place | Shanghai |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | 2-keto-L-gulonic acid kinetic model mixed culture Gluconobacter oxydans Bacillus megaterium Electrical Engineering Materials Science Computer Science Architecture Life Sciences |
| Content Type | Text |
| Resource Type | Article |
| Subject | Multidisciplinary |
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