NDLI: Y-SNP haplogroups related to the Yqh+ heteromorphism in the Mexican northwestern population

Content Provider	Springer Nature Link
Author	ROMO MARTÍNEZ, ENRIQUE JHONATAN MARTÍNEZ CORTÉS, GABRIELA BARAJAS TORRES, REYNA LUCÍA RUBI CASTELLANOS, RODRIGO MAGAÑA TORRES, MARÍA TERESA RANGEL VILLALOBOS, HÉCTOR GONZÁLEZ GARCÍA, JUAN RAMÓN
Copyright Year	2012
Abstract	Morphological variation of the Y chromosome has been observed in different populations. This variation is mostly related to the heteromorphic Yq12 band, which is composed of a variable block of constitutive heterochromatin. The Yqh+ heteromorphism has a worldwide frequency of 2.85% and is considered clinically innocuous. The aim of this study was to identify the ancestry of the Yqh+ heteromorphism present in individuals from western Mexico. For this purpose, 17 Y-chromosome single nucleotide polymorphisms were analysed by multiplex polymerase chain reaction and SNaPshot assays. In 28 Yqh+ males, only five haplogroups were observed; with a haplogroup diversity of 0.4841 ± 0.1094, which was less than that observed in a study of unselected Mexican mestizo population. Differences were specifically conferred by the high frequencies of haplogroups R1b1 and P(xQ,R), and by the absence of the Amerindian haplogroup Q (Q(xQ1a3a) plus Q1a3a) from the Yqh+ group. This study suggests a post-1492 incorporation for Yqh+ chromosomes into the Mexican northwestern population.
Starting Page	297
Ending Page	302
Page Count	6
File Format	PDF
ISSN	00221333
Journal	Journal of Genetics
Volume Number	91
Issue Number	3
e-ISSN	09737731
Language	English
Publisher	Springer-Verlag
Publisher Date	2012-11-29
Publisher Institution	Indian Academy of Sciences
Publisher Place	India
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Y-chromosome single nucleotide polymorphisms haplogroups ancestry Yq12 heteromorphism Life Sciences Microbial Genetics and Genomics Plant Genetics & Genomics Animal Genetics and Genomics Evolutionary Biology
Content Type	Text
Resource Type	Article
Subject	Genetics

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