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| Content Provider | Springer Nature Link |
|---|---|
| Author | Ma, Yanping Li, Mali Zheng, Bo Wang, Ning Gao, Shuang Wang, Lin Qi, Ying Sun, Zhengrong Ruan, Qiang |
| Copyright Year | 2013 |
| Abstract | Transcription of human cytomegalovirus UL/b′ region has been studied extensively for some genes. In this study, transcripts of the UL140 and UL141, two of the UL/b′ genes, were identified in late RNAs of three HCMV isolates using Northern blot hybridization, cDNA library screening and RACE-PCR. At least three transcripts with length of 2800, 2400 and 1700 nt, as well as a group of transcripts of about 1000–1300 nt, were found in this gene region with an accordant 3′ ends. Among the transcripts, two initiated upstream of the start code of the UL140 gene and contained the UL140 and UL141 open reading frame (ORF), one initiated in the middle of the UL140 gene, and could encode short ORFs upstream of the UL141 ORF. A group of transcripts initiated upstream or downstream of the start code of the UL141 gene, and could encode ‘nested’ ORFs, including the UL141 ORF. These ‘nested’ ORFs possess different initiation sites but the same termination site as that of the UL141 ORF. |
| Starting Page | 35 |
| Ending Page | 44 |
| Page Count | 10 |
| File Format | |
| ISSN | 02505991 |
| Journal | Journal of Biosciences |
| Volume Number | 38 |
| Issue Number | 1 |
| e-ISSN | 09737138 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2013-01-23 |
| Publisher Institution | Indian Academy of Sciences |
| Publisher Place | India |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Cytomegalovirus transcription UL140 UL141 Life Sciences Biomedicine general Zoology Plant Sciences Microbiology Cell Biology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Biochemistry, Genetics and Molecular Biology Agricultural and Biological Sciences |
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