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| Content Provider | Springer Nature Link |
|---|---|
| Author | Sarker, Md. Mosharrof Hossain Zhou, Meng Chu Rameshwar, Pranela Haver, John A. |
| Copyright Year | 2013 |
| Abstract | The divergence of protein (Hedgehog) in different organisms remains an unresolved issue to comprehend how the pathway in Hh signaling evolves. Insights into this question can help one identify the key molecules in Hh signaling. This work proposes a protein-associated factor in cells. The development of a non-reductionist theory of cellular functions in medicine is not sufficient. It is necessary to find the parameters with regards to molecules/genes that can elicit functions. This work shows that molecular interactions of gene products can be accomplished by biophysics logic. Defining the protein-associated factors in molecular activities and identifying its roles in molecular transduction are important. A misregulation in molecular switch can account for complex biomolecular consequences. This work shows the potential of the factor on homo-sapiens and unlocks its implications to gene multi-tasking functionality. The associated factor notion should facilitate the medical development in cancer therapeutics. |
| Starting Page | 577 |
| Ending Page | 582 |
| Page Count | 6 |
| File Format | |
| ISSN | 10859195 |
| Journal | Cell Biochemistry and Biophysics |
| Volume Number | 68 |
| Issue Number | 3 |
| e-ISSN | 15590283 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2013-09-15 |
| Publisher Place | Boston |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Associated factor Signal guide Stem cells Biochemistry Pharmacology/Toxicology Biotechnology Cell Biology Biophysics and Biological Physics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Medicine Biochemistry Biophysics |
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