NDLI: Association of Serum Levels of Adipocyte Fatty Acid-Binding Protein and High-Sensitivity C Reactive Protein with Severity of Acute Ischemic Stroke

Content Provider	Springer Nature Link
Author	Huang, Xiang lei
Copyright Year	2014
Abstract	To evaluate the serum levels of adipocyte fatty acid-binding protein (A-FABP) and high-sensitivity C reactive protein (hs-CRP) in patients with acute ischemic stroke (AIS), and correlations among A-FABP, hs-CRP, and AIS, 108 patients with AIS and 86 healthy controls were examined. The levels of hs-CRP and A-FABP were detected by ELISAs. The stroke severity was determined using the modified Rankin scale (mRS). Patients with AIS were divided into those with mild (mRS ≤ 3) and severe disease (mRS > 3). Regression analysis was performed to test association between hs-CRP and A-FABP. Serum levels of hs-CRP and A-FABP were significantly higher in patients with AIS compared with healthy controls. Furthermore, more severe AIS was associated with higher levels of these markers. Regression analysis demonstrated a weak but significant association between A-FABP and hs-CRP. A-FABP and hs-CRP are associated with AIS, and may be involved in the pathogenesis of AIS.
Starting Page	359
Ending Page	361
Page Count	3
File Format	PDF
ISSN	10859195
Journal	Cell Biochemistry and Biophysics
Volume Number	72
Issue Number	2
e-ISSN	15590283
Language	English
Publisher	Springer US
Publisher Date	2014-12-30
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	hs-CRP A-FABP Acute ischemic stroke Biochemistry Pharmacology/Toxicology Biotechnology Cell Biology Biophysics and Biological Physics
Content Type	Text
Resource Type	Article
Subject	Cell Biology Medicine Biochemistry Biophysics

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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