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  1. Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology
  2. Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 10
  3. Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 10, Issue 3, July 2016
  4. Exosomes: Generation, structure, transport, biological activity, and diagnostic application
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Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 11
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 10
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 10, Issue 4, October 2016
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 10, Issue 3, July 2016
Exosomes: Generation, structure, transport, biological activity, and diagnostic application
Expression of FOXP3 and RORγt in CD4$^{+}$ thymocytes of children with congenital heart defects of different severity
Molecular mechanisms of the regulation by kisspeptin of the formation and functional activity of Treg and Th17
Stimulation of dopamine oxidation in liver mitochondria by palmitic acid in the presence of ATP and tert-butylhydroperoxide
Ultrastructural localization of the ROMK potassium channel in rat liver and heart
Emergence of acetylcholine resistance and loss of rhythmic activity associated with the development of hypertension, obesity, and type 2 diabetes
Ultrastructural study of glial gap junctions in the thalamic nuclei of rat
Ca$^{2+}$/H$^{+}$ antiport as a possible mechanism of the Ca$^{2+}$-translocating ATPase functioning in vesicles of bean root nodule’s symbiosome membrane
Glutathione transferase activity of vacuoles, plastids, and tissue extracts of red beetroot
Fluorescence of neurotransmitters and their reception in plant cell
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 10, Issue 2, April 2016
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 10, Issue 1, January 2016
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 9
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 8
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 7
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 6
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 5
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 4
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 3
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 2
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology : Volume 1

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Exosomes: Generation, structure, transport, biological activity, and diagnostic application

Content Provider Springer Nature Link
Author Tamkovich, S. N. Tutav, O. S. Laktiov, P. P.
Copyright Year 2016
Abstract Cells of almost all tissues secrete to the extracellular environment a variety of vesicular structures. The most interesting vesicles are exosomes–microvesicles ranging from 30 to 100 nm in size. These vesicles contain various RNA, including mRNA, microRNA, as well as membrane and cytoplasmic proteins that can be transported in these particles to nearby and distantly located cells of various tissues using physiological fluids (blood, urine, saliva, etc.). Exosomes are necessary for normal functioning of the organism and their repertoire changes during the development of pathologies. This review presents the data on generation, secretion, and transport of exosomes, their structure and roles in normal conditions and in the process of the malignant tumor development. Prospects of the application of exosomal biomarkers for the development of early non-invasive cancer diagnosis are also discussed.
Starting Page 163
Ending Page 173
Page Count 11
File Format PDF
ISSN 19907478
Journal Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology
Volume Number 10
Issue Number 3
e-ISSN 19907494
Language English
Publisher Pleiades Publishing
Publisher Date 2016-08-11
Publisher Place Moscow
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword exosomes microvesicles biomarkers cell-to-cell signaling microRNA proteomic markers Cell Biology
Content Type Text
Resource Type Article
Subject Cell Biology Biochemistry Biophysics
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