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| Content Provider | Springer Nature Link |
|---|---|
| Author | Delton Vandenbroucke, Isabelle Maude, Maureen B. Chen, Huiming Aguirre, Gustavo D. Acland, Gregory M. Anderson, Robert E. |
| Copyright Year | 1998 |
| Abstract | Dogs were born to mothers fed commercial diets low or enriched in n-3 fatty acids and raised on those diets until they were about 50 d old. Retinas were removed, lipids were extracted, and total phospholipids were anlyzed for fatty acid and molecular species composition. Animals from the low n-3 group had significantly lower retinal levels of 22∶6n-3 and higher levels of n-6 fatty acids, especially 20∶4n-6 and 22∶5n-6. There was no difference in the retinal levels of 18∶2n-6, and only small differences were found in saturated and monounsaturated fatty acids. The most dramatic differences in molecular species occurred in 22∶6n-3-22∶6n-3 (4.7 vs. 0.8%) and 18∶0-22∶6n-3 (27.6 vs. 14.4%); total molecular species containing 22∶6n-3 were significantly lower in the low n-3 group (45.5 vs. 24.0%). Molecular species containing 20∶4n-6 and 22∶5n-6 were greater in the low n-3 animals (13.0 vs. 25.7%), as were molecular species containing only saturated and monounsaturated fatty acids (40.8 vs. 35.4%). These results show that modest differences in the amount of n-3 fatty acids in the diets of dogs can have profound effects on the fatty acid and molecular species composition of their retinas. |
| Starting Page | 1187 |
| Ending Page | 1193 |
| Page Count | 7 |
| File Format | |
| ISSN | 00244201 |
| Journal | Lipids |
| Volume Number | 33 |
| Issue Number | 12 |
| e-ISSN | 15589307 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 1998-01-01 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Nutrition Bioorganic Chemistry Medicinal Chemistry Medical Biochemistry Biochemistry Microbial Genetics and Genomics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Organic Chemistry Biochemistry |
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