NDLI: Lower Irritation Potential of Laureth-3 Carboxylate Amino Acid Salt

Content Provider	Springer Nature Link
Author	Ito, Seito Kawata, Jyunichi Kameda, Munekazu Miyazawa, Mitsuo
Copyright Year	2015
Abstract	Sodium laureth sulfate and amino acid type surfactants have been categorized as low-skin irritation chemicals based on results of previous skin irritation tests. However, detergent-induced skin irritation still occurs. Detergents with a low-skin irritation effect are required, since the number of cosmetics for sensitive skin has increased. Therefore, an in vitro method of testing the safety of cosmetics for sensitive skin is required. Skin irritation by anionic surfactants was investigated to determine the effect of laureth-3 carboxylate (polyoxyethylene lauryl carboxymethyl ether) amino acid salt on skin irritation. In addition, sodium laureth sulfate and amino acid type surfactants, regarded as low-irritation surfactants, were also tested for skin irritation. The skin irritation effect of laureth-3 carboxylate lysine salt (Surfactant 1), sodium laureth sulfate (Surfactant 2), and sodium N-lauroyl glutamate (Surfactant 3) were investigated using a reconstructed human cultured epidermal model, LabCyte EPI-MODEL24 6D. Cell viabilities of cultured epidermal cells exposed to Surfactant 1 (5.0 % aq.), Surfactant 2, and Surfactant 3 were 82.0, 45.0 and 19.1 %, respectively. There were significant differences in cell viability upon exposure to 5.0 % aqueous test solutions of the three test chemicals. The results of the current investigation indicate that Surfactant 1 has a low skin-irritation effect.
Starting Page	421
Ending Page	424
Page Count	4
File Format	PDF
ISSN	10973958
Journal	Journal of Surfactants and Detergents
Volume Number	19
Issue Number	2
e-ISSN	15589293
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2015-12-11
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Laureth-3 carboxylate amino acid salt Anionic surfactant Skin irritation LabCyte EPI-MODEL 6-Day cultured model Industrial Chemistry/Chemical Engineering Waste Water Technology Water Pollution Control Water Management Aquatic Pollution Surfaces and Interfaces, Thin Films Polymer Sciences Physical Chemistry
Content Type	Text
Resource Type	Article
Subject	Surfaces, Coatings and Films Physical and Theoretical Chemistry Chemical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Surface and aqueous properties of anionic gemini surfactants having dialkyl amide, carboxyl, and carboxylate groups

Wormlike Micelles in Mixed Amino Acid-Based Anionic Surfactant and Zwitterionic Surfactant Systems

Synthesis and Characterization of Novel Surfactants Based on 2-Hydroxy-4-(Methylthio)Butanoic Acid: 1. Anionic Surfactants

Synthesis of new extended surfactants containing a carboxylate or sulfate polar group

Adsorption, Desorption and Adsolubilization Properties of Mixed Anionic Extended Surfactants and a Cationic Surfactant

Micelle ionization degree of anionic gemini surfactant having N,N-dialkylamide and carboxylate groups

Ethoxy Carboxylate Extended Surfactant: Micellar, Adsorption and Adsolubilization Properties

Synthesis and Surface Properties of Anionic Gemini Surfactants having N-acylamide and Carboxylate Groups

Synthesis and Physico-Chemical Properties of Sodium 3-Oxo-2-(3-(4-sulphonatophenyl)triaz-2-enyl)octadecanoate Anionic Surfactant

Lower Irritation Potential of Laureth-3 Carboxylate Amino Acid Salt

Similar Documents

Surface and aqueous properties of anionic gemini surfactants having dialkyl amide, carboxyl, and carboxylate groups

Wormlike Micelles in Mixed Amino Acid-Based Anionic Surfactant and Zwitterionic Surfactant Systems

Synthesis and Characterization of Novel Surfactants Based on 2-Hydroxy-4-(Methylthio)Butanoic Acid: 1. Anionic Surfactants

Synthesis of new extended surfactants containing a carboxylate or sulfate polar group

Adsorption, Desorption and Adsolubilization Properties of Mixed Anionic Extended Surfactants and a Cationic Surfactant

Micelle ionization degree of anionic gemini surfactant having N,N-dialkylamide and carboxylate groups

Ethoxy Carboxylate Extended Surfactant: Micellar, Adsorption and Adsolubilization Properties

Synthesis and Surface Properties of Anionic Gemini Surfactants having N-acylamide and Carboxylate Groups

Synthesis and Physico-Chemical Properties of Sodium 3-Oxo-2-(3-(4-sulphonatophenyl)triaz-2-enyl)octadecanoate Anionic Surfactant

Lower Irritation Potential of Laureth-3 Carboxylate Amino Acid Salt