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| Content Provider | Springer Nature Link |
|---|---|
| Author | Pianti, Camila B. Sousa Canavez, Juliana M. Srougi, Victor Salvadori, Fernanda Kato, Raphael Ayres, Pedro Paulo R. Srougi, Miguel Camara Lopes, Luiz Heraldo Gattás, Gilka Jorge Figaro Fridman, Cintia Toledo, Fernanda Santana, Isaque Leite, Kátia Ramos Moreira |
| Copyright Year | 2009 |
| Abstract | Bladder cancer (BC) is the fourth most common cancer in the USA. In Brazil, BC represents 3% of the total existing carcinomas in the population and represents the second highest incidence among urological tumors. The majority of bladder cancer cell lines available were derived from Caucasians and established in the seventies or eighties. Thus, neoplasia development in these cells likely occurred in environment conditions vastly different than today. In the present study, we report the establishment and characterization of three Brazilian bladder cancer cell lines (BexBra1, BexBra2, and BexBra4). These cell lines may be helpful for dissecting the genetic and epigenetic aspects that trigger the progression of BC. Moreover, the development of a Brazilian representative of the disease will allow us to investigate the potential inter-racial differences of malignancy-associated phenotypes in bladder cancer. |
| Starting Page | 131 |
| Ending Page | 139 |
| Page Count | 9 |
| File Format | |
| ISSN | 10712690 |
| Journal | In Vitro Cellular & Developmental Biology - Animal |
| Volume Number | 46 |
| Issue Number | 2 |
| e-ISSN | 1543706X |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2009-11-14 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Bladder cancer Establishment Cell lines Animal Genetics and Genomics Cell Culture Stem Cells Developmental Biology Cell Biology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Developmental Biology Medicine |
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