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  1. In Vitro Cellular & Developmental Biology - Animal
  2. In Vitro Cellular & Developmental Biology - Animal : Volume 38
  3. In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 5, May 2002
  4. A kidney epithelial cell line from a bolivian squirrel monkey
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In Vitro Cellular & Developmental Biology - Animal : Volume 53
In Vitro Cellular & Developmental Biology - Animal : Volume 52
In Vitro Cellular & Developmental Biology - Animal : Volume 51
In Vitro Cellular & Developmental Biology - Animal : Volume 50
In Vitro Cellular & Developmental Biology - Animal : Volume 49
In Vitro Cellular & Developmental Biology - Animal : Volume 48
In Vitro Cellular & Developmental Biology - Animal : Volume 47
In Vitro Cellular & Developmental Biology - Animal : Volume 46
In Vitro Cellular & Developmental Biology - Animal : Volume 45
In Vitro Cellular & Developmental Biology - Animal : Volume 44
In Vitro Cellular & Developmental Biology - Animal : Volume 43
In Vitro Cellular & Developmental Biology - Animal : Volume 42
In Vitro Cellular & Developmental Biology - Animal : Volume 41
In Vitro Cellular & Developmental Biology - Animal : Volume 40
In Vitro Cellular & Developmental Biology - Animal : Volume 39
In Vitro Cellular & Developmental Biology - Animal : Volume 38
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 10, November 2002
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 9, October 2002
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 8, September 2002
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 7, July 2002
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 6, June 2002
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 5, May 2002
Long-term in vitro generation of amoebocytes from the Indian horseshoe crab Tachypleus gigas (müller)
A kidney epithelial cell line from a bolivian squirrel monkey
A new cell line from the embryonic tissue of Helicoverpa armigera HBN. (Lepidoptera: Noctuidae)
Simultaneous isolation of endothelial and smooth muscle cells from human umbilical artery or vein and their growth response to low-density lipoproteins
Isolation and molecular characterization of brain microvascular endothelial cells from human brain tumors
Characterization of an epithelial cell line from bovine mammary gland
Histological and ultrastructural regulation in rabbit endometrial explants by estrogen in serum-free culture
Beta blockade induces apoptosis in cultured capillary endothelial cells
Oxygen modulates the growth of skin fibroblasts
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 4, April 2002
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 3, March 2002
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 2, February 2002
In Vitro Cellular & Developmental Biology - Animal : Volume 38, Issue 1, January 2002
In Vitro Cellular & Developmental Biology - Animal : Volume 37
In Vitro Cellular & Developmental Biology - Animal : Volume 36
In Vitro Cellular & Developmental Biology - Animal : Volume 35
In Vitro Cellular & Developmental Biology - Animal : Volume 34
In Vitro Cellular & Developmental Biology - Animal : Volume 33

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A kidney epithelial cell line from a bolivian squirrel monkey

Content Provider Springer Nature Link
Author Scammell, Jonathan G. Tucker, J. Allan King, Judy A. Moore, Charleen M. Wright, James L. Tuck Muller, Cathy M.
Copyright Year 2002
Abstract Squirrel monkeys are the most commonly used New World primates in biomedical research, but in vitro studies are restricted by the limited number of cell lines available from this species. We report here the development and characterization of a continuous, kidney epithelial cell line (SQMK-FP cells) derived from a newborn squirrel monkey. Karyotype was consistent with Bolivian squirrel monkey (submetacentric chromosome pair 15 and acrocentric chromosome pair 16). All cells examined were hyperdiploid with chromosome numbers ranging from 52 to 57. Ultrastructural analysis of SQMK-FP cells revealed the presence of cell junctions with radiating filaments, indicating desmosomes and numerous surface projections containing longitudinally oriented filaments typical of tubular epithelium. Biochemically, SQMK-FP cells exhibit glucocorticoid resistance typical of the squirrel monkey. Glucocorticoid receptor (GR) binding is low in SQMK-FP cells because of high expression of the FK506-binding immunophilin FKBP51 that inhibits GR binding. SQMK-FP cells constitute a tubular epithelial cell line that has biochemical properties characteristic of squirrel monkeys and represent an alternate cell model to B-lymphoblast SML cells to study the biology of the squirrel monkey in vitro.
Starting Page 258
Ending Page 261
Page Count 4
File Format PDF
ISSN 10712690
Journal In Vitro Cellular & Developmental Biology - Animal
Volume Number 38
Issue Number 5
e-ISSN 1543706X
Language English
Publisher Springer-Verlag
Publisher Date 2002-01-01
Publisher Place New York
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword New World primate electron microscopy glucocorticoid receptor immunophilin FKBP51 FKBP52 Cell Biology Developmental Biology Animal Genetics and Genomics Animal Biochemistry Animal Physiology
Content Type Text
Resource Type Article
Subject Cell Biology Developmental Biology Medicine
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