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  1. Journal of Zhejiang University SCIENCE B
  2. Journal of Zhejiang University SCIENCE B : Volume 14
  3. Journal of Zhejiang University SCIENCE B : Volume 14, Issue 8, August 2013
  4. Metabolic remodeling in chronic heart failure
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Journal of Zhejiang University SCIENCE B : Volume 18
Journal of Zhejiang University SCIENCE B : Volume 17
Journal of Zhejiang University SCIENCE B : Volume 16
Journal of Zhejiang University SCIENCE B : Volume 15
Journal of Zhejiang University SCIENCE B : Volume 14
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 12, December 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 11, November 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 10, October 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 9, September 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 8, August 2013
Outcomes research: science and action
Interleukin-17 and acute coronary syndrome
Update of transcatheter valve treatment
Advances in monoclonal antibody application in myocarditis
Metabolic remodeling in chronic heart failure
Effects of rosuvastatin on the production and activation of matrix metalloproteinase-2 and migration of cultured rat vascular smooth muscle cells induced by homocysteine
Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion
A correlation between acute kidney injury and myonecrosis after scheduled percutaneous coronary intervention
Influence of serum adiponectin level and SNP +45 polymorphism of adiponectin gene on myocardial fibrosis
Gorham-Stout syndrome in mainland China: a case series of 67 patients and review of the literature
Risk of cardiac rupture after acute myocardial infarction is related to a risk of hemorrhage
Factors underlying the association of body mass index with serum ALT in Chinese hypertensive adults without known hepatic diseases
Correlation between virus persistent infection and cardic function in patients with dilated cardiomyopathy
Factors associated with decision time for patients with ST-segment elevation acute myocardial infarction
Application of CRT-D in a Marfan syndrome patient with chronic heart failure accompanied by ventricular tachycardia and ventricular fibrillation
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 7, July 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 6, June 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 5, May 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 4, April 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 3, March 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 2, February 2013
Journal of Zhejiang University SCIENCE B : Volume 14, Issue 1, January 2013
Journal of Zhejiang University SCIENCE B : Volume 13
Journal of Zhejiang University SCIENCE B : Volume 12
Journal of Zhejiang University SCIENCE B : Volume 11
Journal of Zhejiang University SCIENCE B : Volume 10
Journal of Zhejiang University SCIENCE B : Volume 9
Journal of Zhejiang University SCIENCE B : Volume 8
Journal of Zhejiang University SCIENCE B : Volume 7
Journal of Zhejiang University SCIENCE B : Volume 6

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Metabolic remodeling in chronic heart failure

Content Provider Springer Nature Link
Author Wang, Jing Guo, Tao
Copyright Year 2013
Abstract Although the management of chronic heart failure (CHF) has made enormous progress over the past decades, CHF is still a tremendous medical and societal burden. Metabolic remodeling might play a crucial role in the pathophysiology of CHF. The characteristics and mechanisms of metabolic remodeling remained unclear, and the main hypothesis might include the changes in the availability of metabolic substrate and the decline of metabolic capability. In the early phases of the disease, metabolism shifts toward carbohydrate utilization from fatty acids (FAs) oxidation. Along with the progress of the disease, the increasing level of the hyperadrenergic state and insulin resistance cause the changes that shift back to a greater FA uptake and oxidation. In addition, a growing body of experimental and clinical evidence suggests that the improvement in the metabolic capability is likely to be more significant than the selection of the substrate.
Starting Page 688
Ending Page 695
Page Count 8
File Format PDF
ISSN 16731581
Journal Journal of Zhejiang University SCIENCE B
Volume Number 14
Issue Number 8
e-ISSN 18621783
Language English
Publisher Springer Berlin Heidelberg
Publisher Date 2013-08-06
Publisher Place Berlin, Heidelberg
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Chronic heart failure (CHF) Metabolic remodeling Metabolic substrate Metabolic capability Biomedicine general
Content Type Text
Resource Type Article
Subject Veterinary Medicine Biochemistry, Genetics and Molecular Biology Pharmacology, Toxicology and Pharmaceutics
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