NDLI: Extracellular volume measurements using bioimpedance spectroscopy-Hanai method and wrist

Content Provider	Springer Nature Link
Author	Jaffrin, Michel Y. Morel, Hélène
Copyright Year	2008
Abstract	A method for extrapolating the extracellular water (ECW) resistance from wrist–ankle resistance at 50 kHz (R $_{50}$) is proposed in this paper, in order to enable 50 kHz impedancemeters to use the BIS-Hanai equation for determination of ECW. Values of R $_{50}$ and the ECW resistance extrapolated at zero frequency R $_{e}$ were measured in a first group of 57 healthy volunteers, using a Xitron 4200 multifrequency impedancemeter and mean values (b) of the ratio R $_{50}$/R $_{e}$ in men and women were used to determine individual values of R $_{e50}$, the ECW resistance extrapolated from R $_{50}$, which were substituted to R $_{e}$ in the BIS-Hanai equation. For validation, the method was compared against ECW measured with the Xitron (V $_{ex}$) in a second group of 31 healthy volunteers, using values of b of first group. Values of R $_{e50}$ in this second group were found to be not significantly different from corresponding values of R $_{e}$ with p-values of Student test of 0.346 for men and 0.300 for women. ECW volumes (V $_{e50}$) calculated from R $_{e50}$ were also found not significantly different from those of the Xitron with Student paired test p values of 0.277 in men and 0.393 in women. Our method gave a better agreement with V $_{ex}$ than two bioimpedance analysis methods from the literature, especially in women. It was also tested on a 50 kHz single frequency impedancemeter (BodyExplorer, Juwell Medical) on a third group of 21 subjects and gave ECW volumes not significantly from those of the Xitron with p = 0.531 for men and 0.096 for women.
Starting Page	77
Ending Page	84
Page Count	8
File Format	PDF
ISSN	01400118
Journal	Medical and Biological Engineering and Computing
Volume Number	47
Issue Number	1
e-ISSN	17410444
Language	English
Publisher	Springer-Verlag
Publisher Date	2008-09-17
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Extracellular water Bioimpedance analysis Computer Applications Imaging Radiology Human Physiology Biomedical Engineering
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering Computer Science Applications

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