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A procedure to simulate coronary artery bypass graft surgery

Content Provider	Springer Nature Link
Author	Cacho, Fernando Doblaré, Manuel Holzapfel, Gerhard A.
Copyright Year	2007
Abstract	In coronary artery bypass graft (CABG) surgery the involved tissues are overstretched, which may lead to intimal hyperplasia and graft failure. We propose a computational methodology for the simulation of traditional CABG surgery, and analyze the effect of two clinically relevant parameters on the artery and graft responses, i.e., incision length and insertion angle for a given graft diameter. The computational structural analyses are based on actual three-dimensional vessel dimensions of a human coronary artery and a human saphenous vein. The analyses consider the structure of the end-to-side anastomosis, the residual stresses and the typical anisotropic and nonlinear vessel behaviors. The coronary artery is modeled as a three-layer thick-walled tube. The finite element method is employed to predict deformation and stress distribution at various stages of CABG surgery. Small variations of the arterial incision have relatively big effects on the size of the arterial opening, which depends solely on the residual stress state. The incision length has a critical influence on the graft shape and the stress in the graft wall. Stresses at the heel region are higher than those at the toe region. The changes in the mechanical environment are severe along all transitions between the venous tissue and the host artery. Particular stress concentrations occur at the incision ends. The proposed computational methodology may be useful in designing a coronary anastomotic device for reducing surgical trauma. It may improve the quantitative knowledge of vessel diseases and serve as a tool for virtual planning of vascular surgery.
Starting Page	819
Ending Page	827
Page Count	9
File Format	PDF
ISSN	01400118
Journal	Medical and Biological Engineering and Computing
Volume Number	45
Issue Number	9
e-ISSN	17410444
Language	English
Publisher	Springer-Verlag
Publisher Date	2007-08-03
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	CABG End-to-side anastomosis Finite element method Intimal hyperplasia Solid mechanics Neurosciences Computer Applications Imaging Radiology Human Physiology Biomedical Engineering
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering Computer Science Applications

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Coronary artery bypass grafting hemodynamics and anastomosis design: a biomedical engineering review

Flow and wall shear stress in end-to-side and side-to-side anastomosis of venous coronary artery bypass grafts

Human Saphenous Vein Coronary Artery Bypass Graft Morphology, Geometry and Hemodynamics

Hemodynamics of End-to-End Femoral Bypass Graft

Analysis of Computational Fluid Dynamics and Particle Image Velocimetry Models of Distal-End Side-to-Side and End-to-Side Anastomoses for Coronary Artery Bypass Grafting in a Pulsatile Flow

Correlation of Hemodynamic Parameters to Endothelial Cell Proliferation in an End to Side Anastomosis

Analysis of blood flow in an out-of-plane CABG model.

A Novel Coronary Artery Bypass Graft Design of Sequential Anastomoses

Flow waveform effects on end-to-side anastomotic flow patterns (1998).

A procedure to simulate coronary artery bypass graft surgery

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Coronary artery bypass grafting hemodynamics and anastomosis design: a biomedical engineering review

Flow and wall shear stress in end-to-side and side-to-side anastomosis of venous coronary artery bypass grafts

Human Saphenous Vein Coronary Artery Bypass Graft Morphology, Geometry and Hemodynamics

Hemodynamics of End-to-End Femoral Bypass Graft

Analysis of Computational Fluid Dynamics and Particle Image Velocimetry Models of Distal-End Side-to-Side and End-to-Side Anastomoses for Coronary Artery Bypass Grafting in a Pulsatile Flow

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A procedure to simulate coronary artery bypass graft surgery