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Computational fluid dynamics-based study of possibility of generating pulsatile blood flow via a continuous-flow VAD

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Computational fluid dynamics-based study of possibility of generating pulsatile blood flow via a continuous-flow VAD

Content Provider	Springer Nature Link
Author	Nammakie, Erfan Niroomand Oscuii, Hanieh Koochaki, Mojtaba Ghalichi, Farzan
Copyright Year	2016
Abstract	Until recent years, it was almost beyond remedy to save the life of end-stage heart failure patients without considering a heart transplant. This is while the need for healthy organs has always far exceeded donations. However, the evolution of VAD technology has certainly changed the management of these patients. Today, blood pumps are designed either pulsatile flow or continuous flow, each of which has its own concerns and limitations. For instance, pulsatile pumps are mostly voluminous and hardly can be used for children. On the other hand, the flow generated by continuous-flow pumps is in contrast with pulsatile flow of the natural heart. In this project, having used computational fluid dynamics, we studied the possibility of generating pulsatile blood flow via a continuous-flow blood pump by adjusting the rotational speed of the pump with two distinct patterns (sinusoidal and trapezoidal), both of which have been proposed and set based on physiological needs and blood flow waveform of the natural heart. An important feature of this study is setting the outlet pressure of the pump similar to the physiological conditions of a patient with heart failure, and since these axial pumps are sensitive to outlet pressures, more secure and reliable results of their performance are achieved. Our results show a slight superiority of a sinusoidal pattern compared to a trapezoidal one with the potential to achieve an adequate pulsatile flow by precisely controlling the rotational speed.
Starting Page	167
Ending Page	178
Page Count	12
File Format	PDF
ISSN	01400118
Journal	Medical and Biological Engineering and Computing
Volume Number	55
Issue Number	1
e-ISSN	17410444
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2016-05-27
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Ventricular assist device CFD Pulsatile flow Hemolysis Human Physiology Biomedical Engineering Imaging Radiology Computer Applications
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering Computer Science Applications

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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