NDLI: On-line monitoring of solutes in dialysate using wavelength-dependent absorption of ultraviolet radiation

Please wait, while we are loading the content...

Combined near-infrared spectroscopy and multifrequency bio-impedance investigation of skin alterations in diabetes patients based on multivariate analyses

Single motor unit analysis from spatially filtered surface electromyogram signals. Part I: Spatial selectivity

Single motor unit analysis from spatially filtered surface electromyogram signals. Part 2: Conduction velocity estimation

Bluetooth wireless database for scoliosis clinics

Biological and mechanical quality of red blood cells cultured from human umbilical cord blood stem cells

Altered impedance during pigment aggregation inXenopus laevis melanophores

Tissue engineering of the intervertebral disc with cultured annulus fibrosus cells using atelocollagen honeycombshaped scaffold with a membrane seal (ACHMS scaffold)

Enhanced functions of osteoblasts on nanostructured surfaces of carbon and alumina

Medical and Biological Engineering and Computing : Volume 41, Issue 2, March 2003

Medical and Biological Engineering and Computing : Volume 41, Issue 1, January 2003

Medical and Biological Engineering and Computing : Volume 40

Medical and Biological Engineering and Computing : Volume 39

Medical and Biological Engineering and Computing : Volume 38

Medical and Biological Engineering and Computing : Volume 37

Medical and Biological Engineering and Computing : Volume 36

Medical and Biological Engineering and Computing : Volume 35

On-line monitoring of solutes in dialysate using wavelength-dependent absorption of ultraviolet radiation

Content Provider	Springer Nature Link
Author	Fridolin, I. Lindberg, L. G.
Copyright Year	2003
Abstract	The aim of the study was to assess the wavelength dependence of the UV absorbance during monitoring of different compounds in the dialysate. UV absorbance was determined by using a double-beam spectrophotometer on dialysate samples taken at pre-determined times during dialysis, over a wavelength range of 180–380 nm. Concentrations of several removed substances, such as urea, creatinine, uric acid, phosphate andβ $_{2}$-microglobulin, were determined in the blood and in the spent dialysate samples using standard laboratory techniques. Millimolar extinction coefficients, for urea, creatinine, monosodium phosphate and uric acid were determined during laboratory bench experiments. The correlation between UV absorbance and substances both in the dialysate and in the blood was calculated at all wavelengths. A time-dependent UV absorbance was determined on the collected dialysate samples from a single dialysis session over a wavelength range of 200–330 nm. The highest contribution from observed compounds relative to the mean value of the absorbance was found around 300 nm and was approximately 70%. The main contribution to the total absorbance from uric acid was confirmed at this wavelength. The highest correlation for uric acid, creatinine and urea was obtained at wavelengths from 280 nm to 320 nm, both in the spent dialysate and in the blood. The wavelength region with the highest correlation for phosphate andβ $_{2}$-microglobulin, with a suitable UV-absorbance dynamic range, was from 300 to 330 nm. In the wavelength range of 220–270 nm the highest absorbance sensitivity for the observed substances was obtained. A suitable wavelength range for instrumental design seems tobe around 290–330 nm. The relatively high correlation between UV absorbance and the substances in the spent dialysate and in the blood indicates that the UV-absorbance technique can estimate the removal of several retained solutes known to accumulate in dialysis patients.
Starting Page	263
Ending Page	270
Page Count	8
File Format	PDF
ISSN	01400118
Journal	Medical and Biological Engineering and Computing
Volume Number	41
Issue Number	3
e-ISSN	17410444
Language	English
Publisher	Springer-Verlag
Publisher Date	2003-01-01
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Haemodialysis Dialysis monitoring Absorption Spectrophotometry Ultraviolet Absorbance Spent dialysate Human Physiology Computer Applications Neurosciences Imaging Radiology Biomedical Engineering
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering Computer Science Applications

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Do Only Small Uremic Toxins, Chromophores, Contribute to the Online Dialysis Dose Monitoring by UV Absorbance?

Dialysate-side urea kinetics. Neural network predicts dialysis dose during dialysis

Whole body urea kinetics

Continuous measurements by impedance of haematocrit and plasma volume variations during dialysis

Optical dialysis adequacy sensor: wavelength dependence of the ultra violet absorbance in the spent dialysate to the removed solutes

Dialysis dose (Kt/V) and clearance variation sensitivity using measurement of ultraviolet-absorbance (on-line), blood urea, dialysate urea and ionic dialysance

Extra-and intracellular volume monitoring by impedance during haemodialysis using Cole-Cole extrapolation

Influence of ionic shifts during dialysis on volume estimations with multifrequency impedance analysis

Blood lines conduct leakage current during haemodialysis: a potential safety risk during first failure, especially for patients with central dialysis catheter as access

On-line monitoring of solutes in dialysate using wavelength-dependent absorption of ultraviolet radiation

Similar Documents

Do Only Small Uremic Toxins, Chromophores, Contribute to the Online Dialysis Dose Monitoring by UV Absorbance?

Dialysate-side urea kinetics. Neural network predicts dialysis dose during dialysis

Whole body urea kinetics

Continuous measurements by impedance of haematocrit and plasma volume variations during dialysis

Optical dialysis adequacy sensor: wavelength dependence of the ultra violet absorbance in the spent dialysate to the removed solutes

Dialysis dose (Kt/V) and clearance variation sensitivity using measurement of ultraviolet-absorbance (on-line), blood urea, dialysate urea and ionic dialysance

Extra-and intracellular volume monitoring by impedance during haemodialysis using Cole-Cole extrapolation

Influence of ionic shifts during dialysis on volume estimations with multifrequency impedance analysis

Blood lines conduct leakage current during haemodialysis: a potential safety risk during first failure, especially for patients with central dialysis catheter as access

On-line monitoring of solutes in dialysate using wavelength-dependent absorption of ultraviolet radiation