NDLI: Body surface Laplacian mapping of atrial depolarization in healthy human subjects

Content Provider	Springer Nature Link
Author	Lian, J. Li, G. Cheng, J. Avitall, B. He, B.
Copyright Year	2002
Abstract	In the present study, we report body surface Laplacian mapping of atrial depolarization under sinus rhythm in 8 healthy male subjects. For each subject, 95 unipolar disk electrodes with inter-electrode distance of 2 cm were used to record simultaneously potential ECGs over the anterior chest. The Laplacian ECG was then estimated during the P wave using a novel spline Laplacian technique. The body surface potential map (BSPM) and body surface Laplacian map (BSLM) at different time instants or time intervals of the P wave were constructed and compared. The present results showed that the BSPMs during the P wave were characterized by the rotation of a pair of positive/negative potential distribution from right to left around the anterior torso. On the other hand, the corresponding BSLMs revealed more spatial details, including two positive activities (denoted as P1 and P2, appeared in all 8 subjects), and three negative activities (denoted as N1, N2, and N3, appeared in 7, 7, and 4 subjects, respectively). The separation of these activities and their evolving patterns were also compared and confirmed by computer simulation using a realistic geometry heart-torso model. The above findings may be directly related to the underlying activation sequence during atrial depolarization in healthy subjects, suggesting the potential clinical applications of the Laplacian ECG technique.
Starting Page	650
Ending Page	659
Page Count	10
File Format	PDF
ISSN	01400118
Journal	Medical and Biological Engineering and Computing
Volume Number	40
Issue Number	6
e-ISSN	17410444
Language	English
Publisher	Springer-Verlag
Publisher Date	2002-01-01
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Body surface Laplacian map Body surface potential map Spline Laplacian ECG Atrial depolarization Electrocardiography Electrophysiology Human Physiology Computer Applications Neurosciences Imaging Radiology Biomedical Engineering
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering Computer Science Applications

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