NDLI: Three-dimensional mapping of brainstem functional lesions

Content Provider	Springer Nature Link
Author	Capozza, M. Iannetti, G. D. Mostarda, M. Cruccu, G.
Copyright Year	2000
Abstract	The human brainstem is a highly complex structure where even small lesions can give rise to a variety of symptoms and outward sings. Localising the area of dysfunction within the brainstem is often a difficult task. To make localisation easier, a neural net system has been developed which uses 72 clinical and neurophysiological data inputs to provide a display (using 5268 voxels) on a three-dimensional model of the human brainstem. The net was trained by means of a back-propagation algorithm, over a pool of 580 example cases. Assessed on 200 test cases, the net correctly localised 83.6% of the target voxels; furthermore the net correctly localised the lesions in 31 out of 37 patients. Because this computer-assisted method provides reliable and quantitative localisation of brainstem areas of dysfunction and can be used as a 3D interactive functional atlas, it is expected to prove useful as a diagnostic tool for assessing focal brainstem lesions.
Starting Page	639
Ending Page	644
Page Count	6
File Format	PDF
ISSN	01400118
Journal	Medical and Biological Engineering and Computing
Volume Number	38
Issue Number	6
e-ISSN	17410444
Language	English
Publisher	Springer-Verlag
Publisher Date	2000-01-01
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Brainstem Neural network 3D mapping Neuroimaging Neurophysiological tests Human Physiology Computer Applications Neurosciences Imaging Radiology Biomedical Engineering
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering Computer Science Applications

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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