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| Content Provider | Springer Nature Link |
|---|---|
| Author | Fidanzio, Andrea Greco, Francesca Gargiulo, Laura Cilla, Savi Sabati, Domenico Cappiello, Massimo Felice, Cinzia Castro, Elisabetta Azario, Luigi Russo, Mariateresa Pompei, Lucia D’Ofrio, Guido Piermattei, Angelo |
| Copyright Year | 2010 |
| Abstract | A practical and accurate generalized in vivo dosimetry procedure has been implemented for Siemens linacs supplying 6, 10, and 15 MV photon beams, equipped with aSi electronic portal imaging devices (EPIDs). The in vivo dosimetry method makes use of correlation ratios between EPID transit signal, s t0(TPR,w,L), and phantom mid-plane dose, D $^{0}$(TPR,w,L), as functions of phantom thickness, w, square field dimensions, L, and tissue-phantom ratio TPR$_{20,10}$. The s t0(TPR,w,L) and D $^{0}$(TPR,w,L) values were defined to be independent of the EPID sensitivity and monitor unit calibration, while their dependence on TPR$_{20,10}$ was investigated to determine a set of generalized correlation ratios to be used for beams with TPR$_{20,10}$ falling in the examined range. This way, other radiotherapy centers can use the method with no need to locally perform the whole set of measurements in solid water phantoms, required to implement it. Tolerance levels for 3D conformal treatments, ranging between ±5 and ±6% according to tumor type and location, were estimated for comparison purposes between reconstructed isocenter dose, D $_{iso}$, and treatment planning system (TPS) computed dose D $_{iso,TPS}$. Finally a dedicated software, interfaceable with record and verify (R&V) systems used in the centers, was developed to obtain in vivo dosimetry results in less than 2 min after beam delivery. |
| Starting Page | 373 |
| Ending Page | 383 |
| Page Count | 11 |
| File Format | |
| ISSN | 01400118 |
| Journal | Medical and Biological Engineering and Computing |
| Volume Number | 49 |
| Issue Number | 3 |
| e-ISSN | 17410444 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2010-11-04 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | aSi EPID In vivo dosimetry Radiotherapy Computer Applications Human Physiology Imaging Radiology Biomedical Engineering |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biomedical Engineering Computer Science Applications |
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