NDLI: Evaluation of an Expanded Disability Status Scale (EDSS) modeling strategy in multiple sclerosis

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Evaluation of an Expanded Disability Status Scale (EDSS) modeling strategy in multiple sclerosis

Content Provider	Springer Nature Link
Author	Cao, Hua Peyrodie, Laurent Agnani, Olivier Cavillon, Fabrice Hautecoeur, Patrick Donzé, Cécile
Copyright Year	2015
Abstract	The Expanded Disability Status Scale (EDSS) is the most widely used scale to evaluate the degree of neurological impairment in multiple sclerosis (MS). In this paper, we report on the evaluation of an EDSS modeling strategy based on recurrence quantification analysis (RQA) of posturographic data (i.e., center of pressure, COP). A total of 133 volunteers with EDSS ranging from 0 to 4.5 participated in this study, with eyes closed. After selection of time delay (τ), embedding dimension (m) as well as threshold (radius, r) to identify recurrent points, several RQA measures were calculated for each COP’s position and velocity data in the mono- and multi-dimensional RQAs. Estimation results lead to the selection of the recurrence rate (RR) of the COP’s position as the most pertinent RQA measure. The performance of the models versus raw and noisy data was higher in the mono-dimensional analysis than in the multi-dimensional. This study suggests that the posturographic signal’s mono-dimensional RQA is a more pertinent method to quantify disability in MS than the multi-dimensional RQA.
Starting Page	1141
Ending Page	1151
Page Count	11
File Format	PDF
ISSN	01400118
Journal	Medical and Biological Engineering and Computing
Volume Number	53
Issue Number	11
e-ISSN	17410444
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2015-09-07
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Multiple sclerosis (MS) Expanded Disability Status Scale (EDSS) Posturographic data Recurrence quantification analysis (RQA) Center of pressure (COP) Mono- and multi-dimensional analyses Human Physiology Biomedical Engineering Imaging Radiology Computer Applications
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering Computer Science Applications

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Automatic Assessment of Expanded Disability Status Scale (EDSS) in Multiple Sclerosis Using a Decision Tree

Automatic Assessment of Expanded Disability Status Scale (EDSS) in Multiple Sclerosis Using a Decision Tree

Expanded disability status scale (edss) estimation in multiple sclerosis from posturographic data (2013).

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PO10-TU-74 Simplified expanded disability status scale (EDSS) table and multiple sclerosis

Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)

Baseline EDSS proportions in MS clinical trials affect the overall outcome and power: A cautionary note

MRI in multiple sclerosis: correlation with expanded disability status scale (EDSS). Mult Scler 5:283–286 (1999)

Evaluation of an Expanded Disability Status Scale (EDSS) modeling strategy in multiple sclerosis

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Evaluation of an Expanded Disability Status Scale (EDSS) modeling strategy in multiple sclerosis