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| Content Provider | Springer Nature Link |
|---|---|
| Author | Oppong, Raymond Kaambwa, Billingsley Nuttall, Jacqui Hood, Kerenza Smith, Richard D. Coast, Joanna |
| Copyright Year | 2011 |
| Abstract | Although EQ-5D has been used in the context of acute cough/lower respiratory tract infections (acute cough/LRTI), it has not been formally validated in this disease area. The primary aim of this study is to assess the construct validity of EQ-5D as a measure for economic evaluation in the context of acute cough/lower respiratory tract infections. Data were collected alongside an observational study of the management of patients with acute cough/LRTI in thirteen European countries. However, the analysis was limited to 349 patients from the UK. Hypotheses were specified a priori and tested in order to establish the construct validity of EQ-5D. Statistical methods used to test the a priori hypotheses included Wilcoxon signed rank sum test, Kruskal-Wallis test, Chi-square test and regression analysis. Most of the relationships that were tested were in line with the a priori hypotheses. The main results indicate that there was a negative relationship between symptom severity scores and EQ-5D, smoking was associated with worse EQ-5D scores and EQ-5D was able to discriminate between patients with headache, interference with normal activities and disturbed sleep. This study also showed that the EQ-5D is moderately responsive in patients with acute cough/LRTI, and is a suitable measure for use in economic evaluation studies of acute cough/LRTI |
| Starting Page | 411 |
| Ending Page | 423 |
| Page Count | 13 |
| File Format | |
| ISSN | 18712584 |
| Journal | Applied Research in Quality of Life |
| Volume Number | 6 |
| Issue Number | 4 |
| e-ISSN | 18712576 |
| Language | English |
| Publisher | Springer Netherlands |
| Publisher Date | 2011-02-03 |
| Publisher Institution | International Society for Quality-of-Life Studies |
| Publisher Place | Dordrecht |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | EQ-5D Validity Cough Lower respiratory tract infections Quality of Life Research Political Science Sociology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Life-span and Life-course Studies |
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