NDLI: Effect of potassium phenosan on structure of plasma membranes of mice liver cells in vitro

Please wait, while we are loading the content...

Biophysics : Volume 62

Biophysics : Volume 61

Biophysics : Volume 60

Biophysics : Volume 59

Biophysics : Volume 58

Biophysics : Volume 58, Issue 6, November 2013

Biophysics : Volume 58, Issue 5, September 2013

Biophysics : Volume 58, Issue 4, July 2013

Biophysics : Volume 58, Issue 3, May 2013

Biophysics : Volume 58, Issue 2, March 2013

Biophysics : Volume 58, Issue 1, January 2013

System-forming functions of bound water in the mechanism of topochemical reactions of formation of ultrathin layers on water surface

Computer modeling of parametric structures of water

Ultrasonic cleavage of DNA in complexes with Ag(I), Cu(II), Hg(II)

Paramagnetic calcium melanins

Singlet-triplet excitation fission in light-harvesting complexes of photosynthetic bacteria and in isolated carotenoids

Highly reactive intermediates in photochemistry of chlorophyll

Peculiarities of growth of the monocellular green algae culture after the influence of electromagnetic field in deuterated water-containing media

Electron transport and transmembrane proton transfer in photosynthetic systems of oxygenic type in Silico

Interrelation between structural state, physicochemical properties and lipid composition in microbial cells

Effect of potassium phenosan on structure of plasma membranes of mice liver cells in vitro

States of succinate dehydrogenase in the organism: Dormant vs. hyperactive (pushed out of equilibrium)

Interaction of a surface-active base with the fraction of membrane-bound Williams’ protons

Physicochemical features of dinitrosyl iron complexes with natural thiol-containing ligands underlying the biological activities of these complexes

Some properties of auditory neuron’s model trained by firing caused by tones modulated by low-frequency noise

Molecular self-organization and multiple equilibrium systems

Chirality as a primary switch of hierarchical levels in molecular biological systems

Lev A. Blumenfeld and spectroscopic studies of photosynthesis at the chair of biophysics, physical faculty, Moscow State University

Biophysics : Volume 57

Biophysics : Volume 56

Biophysics : Volume 55

Biophysics : Volume 54

Biophysics : Volume 53

Biophysics : Volume 52

Biophysics : Volume 51

Effect of potassium phenosan on structure of plasma membranes of mice liver cells in vitro

Content Provider	Springer Nature Link
Author	Chasovskaya, T. E. Mal’tseva, E. L. Palmina, N. P.
Copyright Year	2013
Abstract	The effect of synthetic anti-oxidant potassium phenosan (PP, potassium salt of β-(4-hydroxy-3,5-ditretbutil-phenyl)-propionic acid) on the structural state of the surface (8 Å) and deep (20–22 Å) lipid regions of plasma membranes of mice liver cells was studied by spin probes method in vitro in a wide range of concentrations (10$^{−5}$–10$^{−21}$ M). Two stable free radicals, 5- and 16-doxyl-stearic acids (C$_{5}$ and C$_{16}$), were used as spin probes. The nonlinear polymodal dose-effect dependences were obtained for parameters that characterize the microviscosity of the lipid bilayer (τ$_{c}$) in the site of localization of the probe C$_{16}$, and the order parameter (S), which characterizes the stiffness of the surface layers of lipids in the site of localization of the probe C$_{5}$. Statistically a reliable increase was observed for parameter τ$_{c}$ after addition of PP at concentrations 10$^{−5}$–10$^{−7}$ M and 10$^{−18}$–10$^{−19}$ M, and for parameter S after addition of PP at concentrations 10$^{−6}$–10$^{−7}$ M and 10$^{−13}$–10$^{−15}$ M. Peaks on both dose-effect curves were separated by the intervals of concentrations where PP had no effect on the studied physico-chemical characteristics of biomembranes. For PP concentrations which caused maximal changes in τ$_{c}$ and S, we investigated thermal dependence of these parameters and determined the thermally induced structural transitions. Comparing with control, ultra-low doses of PP (10$^{−13}$–10$^{−15}$ M) and (10$^{−18}$–10$^{−19}$ M) caused an appearance of additional thermally induced structural transition in the surface and deep regions of plasma membrane lipids. The possible role of the interaction of PP molecules with specific binding sites on plasma membranes and formation of nanoparticles of PP in very dilute aqueous solutions are discussed.
Starting Page	78
Ending Page	85
Page Count	8
File Format	PDF
ISSN	00063509
Journal	Biophysics
Volume Number	58
Issue Number	1
e-ISSN	15556654
Language	English
Publisher	SP MAIK Nauka/Interperiodica
Publisher Date	2013-04-22
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	potassium phenosan ultra-low doses spin labels membrane lipid microviscosity order parameter thermoinduced structural transitions in lipids Biophysics and Biological Physics
Content Type	Text
Resource Type	Article
Subject	Biophysics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Effects of low concentrations of synthetic antioxidant phenosan potassium salt on the thermoinduced structural transitions in the protein component of plasma membranes.

Effects of low concentrations of synthetic antioxidant phenosan potassium salt on the thermoinduced structural transitions in the protein component of plasma membranes

Modification of the structure of plasmatic membranes of the liver by the action of α-tocopherol in vitro

Dose dependences of lipid microviscosity of biological membranes induced by synthetic antioxidant potassium phenosan salt.

Dose dependences of lipid microviscosity of biological membranes induced by synthetic antioxidant potassium phenosan salt

Effect of endotoxin on lipid order and motion in erythrocyte membranes.

Structural insights on biologically relevant cationic membranes by ESR spectroscopy

Modification of lipid domains in liver plasmatic membranes by phenosan potassium salt in a wide concentration range in vitro

Studying the effect of Dimebon and NT-1505 on microviscosity of mice brain synaptosomal membranes in vivo by EPR spin labeling method

Effect of potassium phenosan on structure of plasma membranes of mice liver cells in vitro

Similar Documents

Effects of low concentrations of synthetic antioxidant phenosan potassium salt on the thermoinduced structural transitions in the protein component of plasma membranes.

Effects of low concentrations of synthetic antioxidant phenosan potassium salt on the thermoinduced structural transitions in the protein component of plasma membranes

Modification of the structure of plasmatic membranes of the liver by the action of α-tocopherol in vitro

Dose dependences of lipid microviscosity of biological membranes induced by synthetic antioxidant potassium phenosan salt.

Dose dependences of lipid microviscosity of biological membranes induced by synthetic antioxidant potassium phenosan salt

Effect of endotoxin on lipid order and motion in erythrocyte membranes.

Structural insights on biologically relevant cationic membranes by ESR spectroscopy

Modification of lipid domains in liver plasmatic membranes by phenosan potassium salt in a wide concentration range in vitro

Studying the effect of Dimebon and NT-1505 on microviscosity of mice brain synaptosomal membranes in vivo by EPR spin labeling method

Effect of potassium phenosan on structure of plasma membranes of mice liver cells in vitro