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| Content Provider | Springer Nature Link |
|---|---|
| Author | Balakin, V. E. Shemyakov, A. E. Zaichkina, S. I. Rozava, O. M. Smirva, E. N. Romanchenko, S. P. Sorokina, S. S. Strelnikova, N. S. |
| Copyright Year | 2016 |
| Abstract | The dynamics of the growth of Ehrlich ascites carcinoma in mice of the SHK line exposed to hypofractionated high-dose irradiation by a thin scanning proton beam has been analyzed for different irradiation volumes and different time intervals (from 4 to 24 hours) between two 30-Gy fractions. Irradiation of the gross tumor volume and the planned target volume was performed within the Bragg peak; the energy of protons at the outlet of the accelerator ranged from 85 to 100 MeV. Hypofractionated irradiation of the gross tumor volume of Ehrlich ascites carcinoma resulted in a more pronounced antitumor effect than the irradiation of the planned target volume. The effect did not depend on the interval between the irradiation episodes. |
| Starting Page | 682 |
| Ending Page | 686 |
| Page Count | 5 |
| File Format | |
| ISSN | 00063509 |
| Journal | Biophysics |
| Volume Number | 61 |
| Issue Number | 4 |
| e-ISSN | 15556654 |
| Language | English |
| Publisher | Pleiades Publishing |
| Publisher Date | 2016-10-19 |
| Publisher Place | Moscow |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | hypofractionation scanning pencil beam proton therapy Ehrlich ascites carcinoma mice Biological and Medical Physics, Biophysics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biophysics |
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