NDLI: Influence of cosmic radiation on lymphocyte micronucleus, serum lipid peroxide and antioxidation capacity in aircrew members

Content Provider	Springer Nature Link
Author	Chen, Weiru Feng, Yingjin Liu, Jiangkuang Zhang, Haili Guo, Ying Zhang, Yan Duan, Shiying Peng, Xintao Sun, Tianping Jia, Baoshan Zhao, Junxian Li, Hua
Copyright Year	2002
Abstract	This study looks into the influence of cosmic radiation at high altitudes on human bodies. Results reveal that the cytokinesis-block micronuclei (CBMN) and conventional cultured micronuclei in peripheral blood lymphocytes, serum levels of lipid peroxide, Superoxide dismutase, and the total antioxidation capacity by chemical colorimetry all increased significantly in aircrew members. There exists a linear relationship between the CBMN and the average annual effective doses of radiation received or the average annual flying hours. With both of them, a trend shows that the serum lipid peroxide levels increase as well. Either the lipid peroxide or CBMN can sensitively reflect the recent changes in flight load. These findings indicate that cosmic radiation impairs the stability of chromosomes and genome, and induces lipid oxidative damage in aircrews; Lymphocyte CBMN and serum lipid peroxide can be used as monitoring indicators in the cosmic radiation protection for aircrew members.
Starting Page	647
Ending Page	653
Page Count	7
File Format	PDF
ISSN	10016538
Journal	Chinese Science Bulletin
Volume Number	47
Issue Number	8
e-ISSN	18619541
Language	English
Publisher	Science in China Press
Publisher Date	2002-01-01
Publisher Place	Beijing
Access Restriction	Subscribed
Subject Keyword	cosmic radiation aircrew micronucleus lipid peroxide antioxidation capacity Life Sciences Physics Chemistry/Food Science Science Geosciences Engineering
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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