NDLI: Mathematical method in optical molecular imaging

Content Provider	Springer Nature Link
Author	Leng, ChengCai Tian, Jie
Copyright Year	2015
Abstract	Optical molecular imaging is an important technique of studies at molecular level and provides promising tools to non-invasively delineate in vivo physiological and pathological activities at cellular and molecular levels, and it has been widely used for diagnosing, managing diseases, metastasis detection and drug development. From a mathematical perspective, this paper mainly focuses on the forward problem and inverse problem in biological tissues based on the radiative transfer equation (RTE). The forward problem is accustomed to describing photon propagation in biological tissues and the inverse problem is used to reconstruct internal source distribution from the signal detected on the external surface. We also introduce the detailed derivation of the RTE and Robin boundary condition and discretization of the forward problem, along with the reconstruction methods and iterative solution algorithms summarized for the inverse problem. Finally, the current and future challenges of optical molecular imaging are discussed. This survey aims to construct a mathematical method, a state-of-the-art framework for optical molecular imaging, from which future research may benefit.
Starting Page	1
Ending Page	13
Page Count	13
File Format	PDF
ISSN	1674733X
Journal	Science in China Series : Information Sciences
Volume Number	58
Issue Number	3
e-ISSN	18691919
Language	Chinese
Publisher	Science China Press
Publisher Date	2015-01-09
Publisher Place	Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	radiative transfer equation (RTE) regularization method source reconstruction optical molecular imaging mathematical method Information Systems and Communication Service
Content Type	Text
Resource Type	Article
Subject	Computer Science

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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