NDLI: Daily ingestion of tetracycline residue present in pasteurized milk: a public health problem

Content Provider	Springer Nature Link
Author	Albuquerque Fernandes, Sergio Augusto Magnavita, Ana Prudencia Assis Ferrao, Sibelli Passini Barbosa Gualberto, Simone Andrade Faleiro, Amanda Santos Figueiredo, Abdias Jose Matarazzo, Soraia Vanessa
Copyright Year	2013
Abstract	The objective of this study was to evaluate (qualitatively and quantitatively) the occurrence of antibiotic residue in pasteurized milk in Brazil. Pasteurized milk samples (n = 252) were collected monthly from Nov. 2010–Oct. 2011 from 21 commercial establishments (brands). A screening test (Delvotest® SP-NT) was applied to those samples. In positive (n = 19) and/or suspect samples (n = 24), we quantified oxytetracycline (OTC) and tetracycline (TC) by high-performance liquid chromatography with diode array detector (HPLC-DAD). OTCs were detected in all positive samples and TCs in six. In the 24suspected samples, OTCs were detected in 23 and TCs were not found in 8. Of the milk brands evaluated (n = 21), the presence of antibiotic residue was not detected in 4; in the other brands, both positive and suspect samples were verified. Results indicate the presence of antibiotic residue above legal limits. According to actual milk consumption in Brazil (441 mL/kg BW/day), in only 9 of the 17 brands of milk with antibiotic residue, the estimated daily intake was at or less than the maximum recommended by the European Union. The screening test used was effective to identify the presence of antibiotic residue (OTC and TC), confirmed by HPLC-DAD. The OTC is the predominant antimicrobial used by dairy farmers. Ingestion of contaminated milk by OTC and TC can increase the resistance of microorganisms to antibiotics.
Starting Page	3427
Ending Page	3434
Page Count	8
File Format	PDF
ISSN	09441344
Journal	Environmental Science and Pollution Research
Volume Number	21
Issue Number	5
e-ISSN	16147499
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2013-11-17
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Antibiotic residue ingestion Delvotest® SP-NT Oxytetracycline Tetracycline Environment Environmental Chemistry Ecotoxicology Environmental Health Atmospheric Protection/Air Quality Control/Air Pollution Waste Water Technology Water Pollution Control Water Management Aquatic Pollution
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis Pollution Medicine

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