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| Content Provider | Springer Nature Link |
|---|---|
| Author | Duangjitcharoen, Y. Kantachote, D. Ongsakul, M. Poosaran, N. Chaiyasut, C. |
| Copyright Year | 2008 |
| Abstract | A strain of Lactobacillus plantarum SS2 isolated from a fermented star fruit (Averrhoa carambola) beverage product in Thailand has been reported to have some probiotic properties, in vitro. In the present study, its in vivo safety and gastrointestinal survival following oral administration to mice was investigated. The acute toxicity test on ICR mice by force-feeding of a single dose of 10$^{9}$ and 10$^{12}$ cells per mouse over 14 days after ingestion showed no adverse effects related to the normal behavior of the laboratory mouse. Although the weight gains of the dosed mice were lower than the control they were still within normal values. There were no significant differences in liver weight ratio or spleen weight index among tested mice and control mice and no evidence of bacteremia. Live SS2 cells labeled with a fluorescent dye (cFDA-SE) and administered orally at 10$^{9}$ cells per mouse were shown to persist in the gastrointestinal tract for 7 days. Colonies similar to the SS2 were detected in fecal samples from the test mice even though the fecal lactic acid bacterial count showed no significant difference in any mice. The strain SS2 is therefore considered to be a possible alternative choice for an inoculum to produce fermented plant beverages. |
| Starting Page | 315 |
| Ending Page | 321 |
| Page Count | 7 |
| File Format | |
| ISSN | 09593993 |
| Journal | World Journal of Microbiology and Biotechnology |
| Volume Number | 25 |
| Issue Number | 2 |
| e-ISSN | 15730972 |
| Language | English |
| Publisher | Springer Netherlands |
| Publisher Date | 2008-11-07 |
| Publisher Place | Dordrecht |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Fermented plant beverages Probiotic lactic acid bacteria L. plantarum SS2 cFDA-SE ICR mice Microbiology Environmental Engineering/Biotechnology Applied Microbiology Biochemistry Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physiology Medicine Applied Microbiology and Biotechnology Biotechnology |
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