NDLI: Genetic Organization and DNA Sequence of Early Region 4 of Bovine Adenovirus Type 3

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Genetic Organization and DNA Sequence of Early Region 4 of Bovine Adenovirus Type 3

Content Provider	Springer Nature Link
Author	Lee, Joong B. Baxi, Mohit K. Idamakanti, Neeraja Reddy, P. Seshidhar Zakhartchouk, Alexandre N. Pyne, C. Babiuk, Lorne A. Tikoo, Suresh K.
Copyright Year	1998
Abstract	We have identified and sequenced 3614 nucleotides located at the extreme right-end of the bovine adenovirus type 3 (BAV3) genome from map units 89.5–100. Analysis of the sequence revealed an inverted terminal repeat (ITR) of 195 bp, and identified five open reading frames (ORFs) designated ORF1, ORF2, ORF3, ORF4 and ORF5. When compared with known E4 ORFs of other adenoviruses, ORFs 1, 2 and 4, which code for proteins of 143, 69 and 143 amino acids respectively, were found to be unique to BAV3. ORFs 3 and 5, which code for proteins of 268 and 219 amino acids respectively, showed partial homology to the E4 34 kDa protein of human adenovirus 2. Nucleotide sequence analysis also identified two potential TATA boxes upstream of ORF1 and a potential polyadenylation signal downstream of ORF5 suggesting that E4 transcripts may be 3′ co-terminal.
Starting Page	99
Ending Page	100
Page Count	2
File Format	PDF
ISSN	09208569
Journal	Virus Genes
Volume Number	17
Issue Number	1
e-ISSN	1572994X
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	1998-01-01
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Medical Microbiology Virology Plant Sciences
Content Type	Text
Resource Type	Article
Subject	Virology Genetics Medicine Molecular Biology

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