NDLI: Models of data and theoretical hypotheses: a case-study in classical genetics

Content Provider	Springer Nature Link
Author	Vorms, Marion
Copyright Year	2012
Abstract	Linkage (or genetic) maps are graphs, which are intended to represent the linear ordering of genes on the chromosomes. They are constructed on the basis of statistical data concerning the transmission of genes. The invention of this technique in 1913 was driven by Morgan’s group’s adoption of a set of hypotheses concerning the physical mechanism of heredity. These hypotheses were themselves grounded in Morgan’s defense of the chromosome theory of heredity, according to which chromosomes are the physical basis of genes. In this paper, I analyze the 1919 debate between William Castle and Morgan’s group, about the construction of genetic maps. The official issue of the debate concerns the arrangement of genes on chromosomes. However, the disputants tend to carry out the discussions about how one should model the data in order to draw predictions concerning the transmission of genes; the debate does not bear on the data themselves, nor does it focus on the hypotheses explaining these data. The main criteria that are appealed to by the protagonists are simplicity and predictive efficacy. However, I show that both parties’ assessments of the simplicity and predictive efficacy of different ways of modeling the data themselves depend on background theoretical positions. I aim at clarifying how preference for a given model and theoretical commitments articulate.
Starting Page	293
Ending Page	319
Page Count	27
File Format	PDF
ISSN	00397857
Journal	Synthese
Volume Number	190
Issue Number	2
e-ISSN	15730964
Language	English
Publisher	Springer Netherlands
Publisher Date	2012-07-18
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Philosophy of Science Epistemology Logic Philosophy of Language Metaphysics
Content Type	Text
Resource Type	Article
Subject	Philosophy Social Sciences

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