NDLI: Top journals selectivity index and “me-too” drugs

Content Provider	Springer Nature Link
Author	Kissin, Igor Bradley, Edwin L.
Copyright Year	2011
Abstract	To assess the probability of success of an analgesic drug we have proposed a bibliometric indicator, the Top Journals Selectivity Index (TJSI) (Kissin 2011). It represents the ratio (as %) between the number of all types of articles on a particular drug in the top 20 biomedical journals and the number of articles on that drug in all (>5,000) journals covered by Medline over the first 5 years after that drug’s introduction. The aim of this study was to demonstrate that TJSI may be used for the assessment of follow-on drugs (those that follow a first-in-class drug). The study tested two hypotheses. First, TJSI can detect the difference (in the same class) between drugs with distinguishing features and drugs without them (“me-too” drugs) better than other publication indices, i.e., the number of all types of articles on a drug in journals presented by Medline (AJI), and the number of articles covering only randomized controlled trials (RCT). Second, there is a relationship between the TJSI of “me-too” drugs and the order (sequential number) in which those drugs reached the market. The study was based on drug classes approved for marketing between the 1960’s and the early 2000’s. The eight classes that had 4 or more drugs were included for analysis. Five specific indicators were used to determine drug’s distinguishing pharmacological properties. It was found that TJSI can detect the difference between follow-on drugs with distinguishing features and those without them better than the other publication indices (AJI or RCT). Our analysis also demonstrated a negative correlation (r = −0.372, p = 0.014) between the TJSI of drugs without distinguishing features (“me-too” drugs) and the order of the drug’s market entry. This implies that TJSI could be useful for the assessment of situations with multiple market entrants in the same class when a new addition has a questionable value.
Starting Page	131
Ending Page	142
Page Count	12
File Format	PDF
ISSN	01389130
Journal	Scientometrics
Volume Number	91
Issue Number	1
e-ISSN	15882861
Language	English
Publisher	Springer Netherlands
Publisher Date	2011-11-17
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Bibliometrics Biomedical journals Follow-on drugs First-in-class drug Pharmaceutical market Food and Drug Administration Library Science Interdisciplinary Studies Information Storage and Retrieval
Content Type	Text
Resource Type	Article
Subject	Library and Information Sciences Computer Science Applications

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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