NDLI: Associations between 60 SNPs identified by APEX microarray and growth rate, meatiness and selection index in boars

Please wait, while we are loading the content...

The role of chromosomes from homeologous group 5 in regulation of grain hardness and protein content in substitution lines of common wheat cultivar Saratovskaya 29

Fruit set variation associated with apozygotic reproduction in sugar beet Beta vulgaris L.

Polymorphism of microsatellite loci in cultivars and species of pear (Pyrus L.)

Associations between 60 SNPs identified by APEX microarray and growth rate, meatiness and selection index in boars

Revision of the species composition of the wood mice from the genus Sylvaemus from the territory of Rostov oblast using karyological, allozyme and molecular genetic analysis

Genetic variability and the origin of house mouse from the territory of russia and neighboring countries

Polymorphism of the cox1 mtDNA gene from cercarial isolates of the avian schistosome Bilharziella polonica (Trematoda: Schistosomatidae) from Belarussian lakes

Mechanisms sustaining displacements of quantitative trait dominance in spring wheat of various geographical regions

Study of the organization of polytene chromosomes in the nuclei of Drosophila melanogaster pseudonurse cells with the use of the DNA library of the Drosophila orena chromocenter

Polymorphic analysis of mitochondrial 16S rRNA gene of two lizard species in Vietnam

Analysis of transcriptional activity of the Arabidopsis thaliana ornithine-delta-aminotransferase gene promoter

Changes in expression of the genes for chemokines, cytokines, and their receptors in response to selank and its fragments

The 9th World Congress on Genetics Applied to Livestock Production

Russian Journal of Genetics : Volume 47, Issue 4, April 2011

Russian Journal of Genetics : Volume 47, Issue 3, March 2011

Russian Journal of Genetics : Volume 47, Issue 2, February 2011

Russian Journal of Genetics : Volume 47, Issue 1, January 2011

Russian Journal of Genetics : Volume 46

Russian Journal of Genetics : Volume 45

Russian Journal of Genetics : Volume 44

Russian Journal of Genetics : Volume 43

Russian Journal of Genetics : Volume 42

Russian Journal of Genetics : Volume 41

Russian Journal of Genetics : Volume 40

Russian Journal of Genetics : Volume 39

Russian Journal of Genetics : Volume 38

Russian Journal of Genetics : Volume 37

Russian Journal of Genetics : Volume 36

Associations between 60 SNPs identified by APEX microarray and growth rate, meatiness and selection index in boars

Content Provider	Springer Nature Link
Author	Brym, P. Sazav, A. A. Kaminski, S.
Copyright Year	2011
Abstract	A total of 312 boars (201 Landrace and 111 Large White) were genotyped with a custom-made low throughput genotyping microarray (called SNiPORK) based on array primer extension (APEX) technology. The results were used to association studies between genotyped SNP markers and daily gains, meat content and selection index. Among the 60 SNP markers analyzed, 14 of them showed statistically significant associations between the genotype and the level of at least one trait. In order to find extremely beneficial or unfavorable intergenic diplotype combinations, 5 SNP markers were selected: CAST A499C, MYF6 T255C, PKLR C384T, SFRS1 C1146T and TNNT3 T153C, which showed statistically significant associations at P ≤ 0.01 within one of the traits and the frequency of homozygotes with a minor allele of at least 0.1. Among 10 possible permutations, statistically significant associations were found only for a combination of SNP markers in TNNT3 × SFRS1 genes and, interestingly, for all combinations with SNP located within the calpastatin (CAST) gene commonly known as a gene influencing pork quality traits. This study also found that CAST allele A (which is beneficial for pork tenderness) is also favorable for growth rate. This effect is clearly increased with additive alleles C of myogenic factor MYF6 and troponin T3 (TNNT3) and is decreased with each allele T from serine rich splicing factor 1 (SFRS1) gene. For meat content, the most favorable genotype of calpastatin gene was AC, the effect of which was generally increased with each C allele of MYF6 and TNNT3 and decreased with each allele T from SFRS1 and PKLR (puruvate kinase) genes, respectively. The calpastatin AC genotype seemed to be beneficial for selection index, although in combination with the CC genotype of troponin T3, calpastatin genotypes AA and CC reached higher values. In the case of the combination of genotypes TNNT3 × SFRS1, the most preferable for all analyzed traits is the CC genotype of TNNT3, especially in combination with CT or CC genotypes in the SFRS1 gene. We conclude that searching for interaction effects between candidate SNPs (even of moderate influence) may lead to interesting and valuable findings enabled better understanding and applications of SNPs in pork yield and quality improvement programmes.
Starting Page	571
Ending Page	578
Page Count	8
File Format	PDF
ISSN	10227954
Journal	Russian Journal of Genetics
Volume Number	47
Issue Number	5
e-ISSN	16083369
Language	English
Publisher	SP MAIK Nauka/Interperiodica
Publisher Date	2011-05-15
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Microbial Genetics and Genomics Animal Genetics and Genomics Human Genetics
Content Type	Text
Resource Type	Article
Subject	Genetics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Additive effects of 19 porcine SNPs on growth rate, meat content and selection index

Associations between the prolactin receptor gene polymorphism and reproductive traits of boars

Different evolutionary patterns of SNPs between domains and unassigned regions in human protein-coding sequences

Associations between polymorphisms in the NICD domain of bovine NOTCH1 gene and growth traits in Chinese Qinchuan cattle

Novel SNPs in the bovine Transmembrane protein 18 gene, their linkage and their associations with growth traits in Nanyang cattle

Human testis-specific genes are under relaxed negative selection

Population genetic structure of wild boars in the West Balkan region

Two novel SNPs in the coding region of bovine VDR gene and their associations with growth traits

Genome wide association study SNPs in the human genome diversity project samples: does selection affect unlinked SNPs with shared trait associations?

Associations between 60 SNPs identified by APEX microarray and growth rate, meatiness and selection index in boars

Similar Documents

Additive effects of 19 porcine SNPs on growth rate, meat content and selection index

Associations between the prolactin receptor gene polymorphism and reproductive traits of boars

Different evolutionary patterns of SNPs between domains and unassigned regions in human protein-coding sequences

Associations between polymorphisms in the NICD domain of bovine NOTCH1 gene and growth traits in Chinese Qinchuan cattle

Novel SNPs in the bovine Transmembrane protein 18 gene, their linkage and their associations with growth traits in Nanyang cattle

Human testis-specific genes are under relaxed negative selection

Population genetic structure of wild boars in the West Balkan region

Two novel SNPs in the coding region of bovine VDR gene and their associations with growth traits

Genome wide association study SNPs in the human genome diversity project samples: does selection affect unlinked SNPs with shared trait associations?

Associations between 60 SNPs identified by APEX microarray and growth rate, meatiness and selection index in boars