NDLI: The structure and evolution of the MaSMC4 gene of common vole Microtus arvalis (Arvicolidae, Rodentia)

Content Provider	Springer Nature Link
Author	Pavlova, S. V. Elisafenko, E. A. Zakian, S. M.
Copyright Year	2007
Abstract	In eukaryotes, the SMC (Structural Maintenance of Chromosomes) gene family is represented by at least six genes. Some of these genes have tissue-specific homologs. Eukaryotic SMC structural proteins are the members of biochemical complexes responsible for cohesion of sister chromatids, recombination, repair, regulation of gene expression, and formation of mitotic chromosomes. In the present study, the structure of the SMC4 subfamily gene was examined in common vole Microtus arvalis. Comparative analysis of rodent (M. arvalis, Mus musculus, and Rattus norvegicus), human, and Xenopus laevis SMC4 orthologous genes was carried out, and the main patterns of their organization and regulation were established. The SMC4 genes contain 24 exons; open reading frame starts at exon 2. The SMC4 5′ regions contain the CpG islands, extending in the region of exon-intron 1 and exon 2. The SMC4 genes are characterized by the presence of multiple transcription startpoints. The region of the major transcription startpoint contains the INR CCA$_{+1}$TTTT element. The SMC4 5′ region is characterized by the presence of putative binding site for basal transcription factor Sp1 and factor E2F, typical of the genes induced in the G1/S phase of the cell cycle. The divergence level of the SMC4 coding region was examined. The mean Ka/Ks ratio for the SMC4 genes examined was 0.123. The region of exon 2 was found to be the most variable (Ka/Ks = 0.715), while the most conservative was the region coding for the C-globular domain, which contained the DA box (Ka/Ks = 0.024).
Starting Page	106
Ending Page	115
Page Count	10
File Format	PDF
ISSN	10227954
Journal	Russian Journal of Genetics
Volume Number	43
Issue Number	2
e-ISSN	16083369
Language	English
Publisher	Nauka/Interperiodica
Publisher Date	2007-01-01
Publisher Place	Moscow
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Human Genetics Animal Genetics and Genomics Microbial Genetics and Genomics
Content Type	Text
Resource Type	Article
Subject	Genetics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

The complete mitochondrial genome of the common vole, Microtus arvalis (Rodentia: Arvicolinae)

Comparative analysis of the MSAT-160 repeats in four species of common vole (Microtus, Arvicolidae)

Factors of maintaining chromosome polymorphism in common vole Microtus arvalis pallas, 1779: Reduced fertility and meiotic drive

Food deprivation in the common vole (Microtus arvalis) and the tundra vole (Microtus oeconomus)

Comparative chromosome and mitochondrial DNA analyses and phylogenetic relationships within common voles (Microtus, Arvicolidae)

Molecular genetic characterization of the regulatory region of the Xist gene in the common vole Microtus rossiaemeridionalis

Investigation of the Tsix gene regulatory region in vole Microtus rossiaemeridionalis

Distribution of L1-retroposons on the giant sex chromosomes of Microtus cabrerae (Arvicolidae, Rodentia): functional and evolutionary implications

Chromosomal evolution of Arvicolinae (Cricetidae, Rodentia). I. The genome homology of tundra vole, field vole, mouse and golden hamster revealed by comparative chromosome painting

The structure and evolution of the MaSMC4 gene of common vole Microtus arvalis (Arvicolidae, Rodentia)

Similar Documents

The complete mitochondrial genome of the common vole, Microtus arvalis (Rodentia: Arvicolinae)

Comparative analysis of the MSAT-160 repeats in four species of common vole (Microtus, Arvicolidae)

Factors of maintaining chromosome polymorphism in common vole Microtus arvalis pallas, 1779: Reduced fertility and meiotic drive

Food deprivation in the common vole (Microtus arvalis) and the tundra vole (Microtus oeconomus)

Comparative chromosome and mitochondrial DNA analyses and phylogenetic relationships within common voles (Microtus, Arvicolidae)

Molecular genetic characterization of the regulatory region of the Xist gene in the common vole Microtus rossiaemeridionalis

Investigation of the Tsix gene regulatory region in vole Microtus rossiaemeridionalis

Distribution of L1-retroposons on the giant sex chromosomes of Microtus cabrerae (Arvicolidae, Rodentia): functional and evolutionary implications

Chromosomal evolution of Arvicolinae (Cricetidae, Rodentia). I. The genome homology of tundra vole, field vole, mouse and golden hamster revealed by comparative chromosome painting

The structure and evolution of the MaSMC4 gene of common vole Microtus arvalis (Arvicolidae, Rodentia)