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| Content Provider | Springer Nature Link |
|---|---|
| Author | Micó, Victor Martín, Roberto Lasunción, Miguel A. Ordovás, Jose M. Daimiel, Lidia |
| Copyright Year | 2016 |
| Abstract | The recent description of the presence of exogenous plant microRNAs from rice in human plasma had profound implications for the interpretation of microRNAs function in human health. If validated, these results suggest that food should not be considered only as a macronutrient and micronutrient supplier but it could also be a way of genomic interchange between kingdoms. Subsequently, several studies have tried to replicate these results in rice and other plant foods and most of them have failed to find plant microRNAs in human plasma. In this scenario, we aimed to detect plant microRNAs in beer and extra virgin olive oil (EVOO) - two plant-derived liquid products frequently consumed in Spain - as well as in human plasma after an acute ingestion of EVOO. Our hypothesis was that microRNAs present in beer and EVOO raw material could survive manufacturing processes, be part of these liquid products, be absorbed by human gut and circulate in human plasma. To test this hypothesis, we first optimized the microRNA extraction protocol to extract microRNAs from beer and EVOO, and then tried to detect microRNAs in those samples and in plasma samples of healthy volunteers after an acute ingestion of EVOO. |
| Starting Page | 102 |
| Ending Page | 108 |
| Page Count | 7 |
| File Format | |
| ISSN | 09219668 |
| Journal | Plant Foods for Human Nutrition |
| Volume Number | 71 |
| Issue Number | 1 |
| e-ISSN | 15739104 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2016-02-12 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Beer Extra virgin olive oil Plant microRNAs Next generation sequencing Food Science Chemistry/Food Science Nutrition Ecology Plant Physiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Food Science |
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