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| Content Provider | Springer Nature Link |
|---|---|
| Author | Zhuang, Ziheng Lv, Ting Li, Min Zhang, Yusi Xue, Ting Yang, Linsong Liu, Hui Zhang, Weiming |
| Copyright Year | 2014 |
| Abstract | Nymphaea hybrid, a water lily from the Nymphaeaceae family, has been found to exhibit some in vivo beneficial effects. In the present study we investigated the lifespan-extending effects of Nymphaea hybrid root extract in the nematode Caenorhabditis elegans. We found that Nymphaea hybrid root extract significantly extended the lifespan of C.elegans and improved its locomotion during aging. Moreover, Nymphaea hybrid root extract increased the resistance of C.elegans to both heat stress and oxidative stress. We found that the ability of Nymphaea hybrid root extract to increase lifespan was independent of its antimicrobial effects and was probably associated with its effects on the reproduction of C.elegans. In addition, the lifespan-extending effects of Nymphaea hybrid root extract were found to be dependent on the insulin/IGF signaling pathway. We also found that total flavones of Nymphaea hybrid could increase survival of C.elegans in both normal and adverse conditions, indicating that total flavones comprise the major fractions with lifespan-extending effects. Therefore, Nymphaea hybrid root extract has lifespan-extending effects in C.elegans and could be developed as a functional food. |
| Starting Page | 304 |
| Ending Page | 309 |
| Page Count | 6 |
| File Format | |
| ISSN | 09219668 |
| Journal | Plant Foods for Human Nutrition |
| Volume Number | 69 |
| Issue Number | 4 |
| e-ISSN | 15739104 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2014-11-01 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Lifespan-extending effects Nymphaea hybrid Caenorhabditis elegans Stress resistance Total flavones Food Science Chemistry/Food Science Nutrition Ecology Plant Physiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Food Science |
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