NDLI: On the Evolution of Primitive Genetic Codes

Content Provider	Springer Nature Link
Author	Weberndorfer, Günter Hofacker, Ivo L. Stadler, Peter F.
Copyright Year	2003
Abstract	The primordial genetic code probably has been a drastically simplifiedancestor of the canonical code that is used by contemporary cells. In orderto understand how the present-day code came about we first need to explainhow the language of the building plan can change without destroying theencoded information. In this work we introduce a minimal organism modelthat is based on biophysically reasonable descriptions of RNA and protein,namely secondary structure folding and knowledge based potentials. Theevolution of a population of such organism under competition for a commonresource is simulated explicitly at the level of individual replicationevents. Starting with very simple codes, and hence greatly reduced aminoacid alphabets, we observe a diversification of the codes in mostsimulation runs. The driving force behind this effect is the possibility toproduce fitter proteins when the repertoire of amino acids is enlarged.
Starting Page	491
Ending Page	514
Page Count	24
File Format	PDF
ISSN	01696149
Journal	Origins of Life and Evolution of Biospheres
Volume Number	33
Issue Number	4-5
e-ISSN	15730875
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2003-01-01
Publisher Place	Dordrecht
Access Restriction	Subscribed
Subject Keyword	Organic Chemistry Geochemistry Biochemistry
Content Type	Text
Resource Type	Article
Subject	Medicine Ecology, Evolution, Behavior and Systematics Space and Planetary Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Chemical Reduction of Phosphate on the Primitive Earth

Reduction and Activation of Phosphate on the Primitive Earth

The Evolution of the Genetic Code Revisited

The Early Phases of Genetic Code Origin: Conjectures on the Evolution of Coded Catalysis

Directed Molecular Evolution

Primitive Molecular Machine Scenario for the Origin of the Three Base Codon Composition

The Lipid World

State of the Journal

On the Plausibility of a UV Transparent Biochemistry

On the Evolution of Primitive Genetic Codes

Similar Documents

Chemical Reduction of Phosphate on the Primitive Earth

Reduction and Activation of Phosphate on the Primitive Earth

The Evolution of the Genetic Code Revisited

The Early Phases of Genetic Code Origin: Conjectures on the Evolution of Coded Catalysis

Directed Molecular Evolution

Primitive Molecular Machine Scenario for the Origin of the Three Base Codon Composition

The Lipid World

State of the Journal

On the Plausibility of a UV Transparent Biochemistry

On the Evolution of Primitive Genetic Codes