NDLI: Disorders of Autonomic Control of Microcirculation in Explosion-Induced Coal-Mine Trauma: Experimental Modeling, Pathogenetic Analysis, and Pharmacological Correction

Please wait, while we are loading the content...

Effects of Modulation of the Activity of the Autonomic Nervous System on the Efficiency of Liposomal Sandostatin in the Treatment of Experimental Pancreatitis

Disorders of Autonomic Control of Microcirculation in Explosion-Induced Coal-Mine Trauma: Experimental Modeling, Pathogenetic Analysis, and Pharmacological Correction

Igor' S. Magura (on his 75th Birthday)

Neurophysiology : Volume 35, Issue 5, September 2003

Neurophysiology : Volume 35, Issue 3-4, May 2003

Neurophysiology : Volume 35, Issue 2, March 2003

Neurophysiology : Volume 35, Issue 1, January 2003

Neurophysiology : Volume 34

Neurophysiology : Volume 33

Neurophysiology : Volume 32

Neurophysiology : Volume 31

Neurophysiology : Volume 30

Neurophysiology : Volume 29

Disorders of Autonomic Control of Microcirculation in Explosion-Induced Coal-Mine Trauma: Experimental Modeling, Pathogenetic Analysis, and Pharmacological Correction

Content Provider	Springer Nature Link
Author	Yel'skii, V. N. Krivobok, G. K. Talalayenko, A. N. Zakharov, V. I.
Copyright Year	2003
Abstract	We modeled the consequences of explosion-induced coal-mine trauma, ECMT, i.e., contusion, intoxication by explosion products, burns, emotional stress, etc., in rats using a specially developed device. ECMT was produced by a dosed explosion of a methane-air mixture. In addition, the device allowed us to model effects of coal-mine occupational factors, CMOF (high air pressure, temperature, and humidity, high contents of dust and alien gases in the air, and intensive physical loading). We examined modifications of microcirculation in the vessels of the abdominal cavity (mesenterial vessels) after ECMT and after such a trauma aggravated by the premorbid action of CMOF (for 1 h daily over 14 days). The long-lasting influence of CMOF evoked noticeable vasoconstriction and a drop in the volume velocity of blood flow through the mesenteric vessels. Both complicated and noncomplicated ECMT resulted in significant dilatation of the mesenteric vessels (their mean diameter increased in 1 h by about 40% as compared with the norm) and an increase in the volume blood flow velocity (by 71 and 41% as compared with the norm, respectively). Injections of 3 mg/kg diazepam (i.p., immediately after ECMT) considerably corrected the shifts of the pressure in and linear velocity of blood flow through the microvessels under study, whereas their diameter and the volume flow velocity remained increased (the former, somewhat, and the latter, significantly). The mechanisms of disorders of regional circulation evoked by the actions of ECMT and CMOF in the visceral microvessels (with special attention to metabolic factors, which evoke vasodilation), the importance of the phenomenon of blood sequestration in these vessels to the clinical course of ECMT, and approaches for pharmacological correction of the above disorders by drugs of the benzodiazepine family are discussed.
Starting Page	450
Ending Page	456
Page Count	7
File Format	PDF
ISSN	00902977
Journal	Neurophysiology
Volume Number	35
Issue Number	6
e-ISSN	15739007
Language	English
Publisher	Kluwer Academic Publishers-Plenum Publishers
Publisher Date	2003-01-01
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Neurosciences
Content Type	Text
Resource Type	Article
Subject	Neuroscience Physiology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Non-Pharmacological Correction of Impaired Microcirculation in Children with Diabetic Polyneuropathy

Disorders of Transmission via a Peripheral Nerve Related to Experimental Diabetic Peripheral Neuropathy in Rats: Possibilities for Pharmacological Correction

A novel explosion-proof walking system: Twin dual-motor drive tracked units for coal mine rescue robots

Three-dimensional geoscience modeling and simulation of gas explosion in coal mine

Neurophysiological and Neurochemical Mechanisms Underlying Depression Disorders and Search for New Directions of Treatment

Vestibular Dysfunctions and Mental/Autonomic Disorders Related to Cerebral Ischemia against the Background of Cervical Osteochondrosis: Pathogenetically Oriented Correction

First Series of Coal-Dust Explosion Tests in the Experimental Mine

Coal-Dust Explosion Tests in the Experimental Mine 1913-1918, Inclusive

Disorders of Autonomic Control under Conditions of Long-Term Psychoemotional Stress: a Risk Factor and a Predictor of Unfavorable Clinical Course of Cerebral Insult

Disorders of Autonomic Control of Microcirculation in Explosion-Induced Coal-Mine Trauma: Experimental Modeling, Pathogenetic Analysis, and Pharmacological Correction

Similar Documents

Non-Pharmacological Correction of Impaired Microcirculation in Children with Diabetic Polyneuropathy

Disorders of Transmission via a Peripheral Nerve Related to Experimental Diabetic Peripheral Neuropathy in Rats: Possibilities for Pharmacological Correction

A novel explosion-proof walking system: Twin dual-motor drive tracked units for coal mine rescue robots

Three-dimensional geoscience modeling and simulation of gas explosion in coal mine

Neurophysiological and Neurochemical Mechanisms Underlying Depression Disorders and Search for New Directions of Treatment

Vestibular Dysfunctions and Mental/Autonomic Disorders Related to Cerebral Ischemia against the Background of Cervical Osteochondrosis: Pathogenetically Oriented Correction

First Series of Coal-Dust Explosion Tests in the Experimental Mine

Coal-Dust Explosion Tests in the Experimental Mine 1913-1918, Inclusive

Disorders of Autonomic Control under Conditions of Long-Term Psychoemotional Stress: a Risk Factor and a Predictor of Unfavorable Clinical Course of Cerebral Insult

Disorders of Autonomic Control of Microcirculation in Explosion-Induced Coal-Mine Trauma: Experimental Modeling, Pathogenetic Analysis, and Pharmacological Correction