NDLI: Molecular cloning, chromosomal location and expression pattern of porcine CIDEa and CIDEc

Content Provider	Springer Nature Link
Author	Li, Y. H. Lei, T. Chen, X. D. Xia, T. Peng, Y. Long, Q. Q. Zhang, J. Feng, S. Q. Zhou, L. Yang, Z. Q.
Copyright Year	2008
Abstract	Cell death-inducing DFF45-like effectors a and c (CIDEa and CIDEc) are two members of the novel CIDE family of apoptosis-inducing factors. Except as pro-apoptotic proteins, it has been reported that CIDEa and CIDEc could be involved in lipid or fat metabolism. Here we first reported the cDNA cloning, chromosome mapping and expression analysis of CIDEa and CIDEc in pigs. Sequence analysis showed that porcine CIDEa contains an open reading frame of 660 bp, which encodes 219 amino acids, and CIDEc contains a coding region of 717 bp that encodes 238 amino acids. The deduced amino acid sequence of porcine CIDEa and CIDEc shows high similarities to their corresponding human and mouse homologues. Radiation hybrid mapping demonstrated that porcine CIDEa and CIDEc are located at chromosome 6q21-26 and 13q31 respectively, syntenic with the loci of their corresponding homologues on human chromosomes. Tissue distribution analysis indicated that porcine CIDEa and CIDEc mRNAs are co-expressed in various tissues. Both of them were highly expressed in white adipose tissue, and CIDEc mRNA was also expressed at relatively high level in porcine small intestine, lymph and brain. Furthermore, CIDEa and CIDEc mRNA level in white adipose tissues and liver were significantly higher in obese pigs than in their lean counterparts. Our studies provide basic molecular information useful for the further investigation on the function of the two genes, which will be helpful in better understanding of the roles of CIDEs in lipid metabolism.
Starting Page	575
Ending Page	582
Page Count	8
File Format	PDF
ISSN	03014851
Journal	Molecular Biology Reports
Volume Number	36
Issue Number	3
e-ISSN	15734978
Language	English
Publisher	Springer Netherlands
Publisher Date	2008-03-03
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Chromosomal localization CIDEa CIDEc Cloning Expression pattern Pigs Animal Biochemistry Animal Anatomy / Morphology / Histology
Content Type	Text
Resource Type	Article
Subject	Genetics Medicine Molecular Biology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Molecular cloning, expression patterns and subcellular localization of porcine TMCO1 gene

Cloning, chromosomal localization, expression profile and association analysis of the porcine WNT10B gene with backfat thickness

The chromosomal localization, expression pattern and polymorphism analysis of porcine FSCN1 gene differently expressed from LongSAGE library

Porcine γ-synuclein: molecular cloning, expression analysis, chromosomal localization and functional expression

Molecular characterization, chromosomal localization, expression profile and association analysis with carcass traits of the porcine dickkopf homolog1 gene

Partial molecular cloning, characterization, and analysis of the subcellular localization and expression patterns of the porcine OTUB1 gene

Molecular cloning and expression analysis of IFN-β promoter stimulator 1 in Tibetan pigs

Cloning, chromosomal localization, SNP detection and association analysis of the porcine IRS-1 gene

Genomic organization, alternative splicing and tissues expression of porcine CREB3L4 gene

Molecular cloning, chromosomal location and expression pattern of porcine CIDEa and CIDEc

Similar Documents

Molecular cloning, expression patterns and subcellular localization of porcine TMCO1 gene

Cloning, chromosomal localization, expression profile and association analysis of the porcine WNT10B gene with backfat thickness

The chromosomal localization, expression pattern and polymorphism analysis of porcine FSCN1 gene differently expressed from LongSAGE library

Porcine γ-synuclein: molecular cloning, expression analysis, chromosomal localization and functional expression

Molecular characterization, chromosomal localization, expression profile and association analysis with carcass traits of the porcine dickkopf homolog1 gene

Partial molecular cloning, characterization, and analysis of the subcellular localization and expression patterns of the porcine OTUB1 gene

Molecular cloning and expression analysis of IFN-β promoter stimulator 1 in Tibetan pigs

Cloning, chromosomal localization, SNP detection and association analysis of the porcine IRS-1 gene

Genomic organization, alternative splicing and tissues expression of porcine CREB3L4 gene

Molecular cloning, chromosomal location and expression pattern of porcine CIDEa and CIDEc