NDLI: Effects of shear-dependent transport properties on lumen surface concentration of LDL particles in stenosed carotid artery

Content Provider	Springer Nature Link
Author	Nematollahi, Ali Shirani, Ebrahim Sadeghi, Mahmood Reza Mirzaee, Iraj
Copyright Year	2015
Abstract	Growth of stenosis is mainly due to the high concentration of plasma lipoprotein such as low density lipoprotein (LDL) near the art ery walls. Accurate prediction of LDL concentration especially near the stenosis and where the shear stress is low, can help to predict the plaque growth. In this paper, a novel model is introduced to predict the LDL concentration near a plaque. This model is based on variable diffusion coefficient of LDL due to the non-Newtonian behavior of the blood flow in low shear stress regions such as flow around plaques. The new model for diffusion coefficient consists of two parts: the stationary and the shear- induced particle diffusivity due to rotation of red blood cells. The results show that the new model predicts the LDL concentration well and unlike the constant diffusion coefficient which is used by others, produces more physical and meaningful results.
Starting Page	1733
Ending Page	1746
Page Count	14
File Format	PDF
ISSN	00256455
Journal	Meccanica
Volume Number	50
Issue Number	7
e-ISSN	15729648
Language	English
Publisher	Springer Netherlands
Publisher Date	2015-02-06
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Atherosclerosis Mass transfer Non-Newtonian fluid Mechanics Civil Engineering Automotive Engineering Mechanical Engineering
Content Type	Text
Resource Type	Article
Subject	Mechanics of Materials Condensed Matter Physics Mechanical Engineering

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