NDLI: Palygorskite organophilic for dermopharmaceutical application

Content Provider	Springer Nature Link
Author	Gois da Silva, Mirna Lucia Fortes, Amanda Campos Oliveira, Marília Evelyn Rodrigues Freitas, Rivelilson Mendes Silva Filho, Edson C. La Roca Soares, Monica Felts Soares Sobrinho, José Lamartine Silva Leite, Cleide Maria
Copyright Year	2013
Abstract	Due to the growing interest of the population in natural treatments, the clays represent a good alternative to the treatment of wounds. Its modification by organophilization happens when the same inorganic cations are exchanged for organic cations of the surfactant used in the process. Thus, the clay has the properties of its surface modified from being hydrophilic to hydrophobic, improving its functionality on the skin. In order to determine changes in surface palygorskite and to assess its healing action, this clay was organophilizated by two cationic surfactants: dimethyl benzyl ammonium chloride alkyl, and cetyl trimethyl ammonium chloride, and characterized by sieve analysis, property flow, test oil adsorption, and the techniques of X-ray fluorescence, X-ray diffraction, infrared Fourier transform, thermogravimetric analysis, scanning calorimetry—differential and histological of cutaneous wounds in rats. The results indicate that the attapulgite has good rheological properties, a high capacity of adsorption of oil, and the presence of clay minerals that reduce inflammation. The analysis by X-ray fluorescence is not observing any change in the crystal structure of palygorskite organophilizated but through infrared spectroscopy Fourier transform, verifying the interaction and incorporation of the clay ammonium salts, as well as thermoanalytical analysis also suggests that the organophilic process reduces the hydrophilic character of palygorskite. The histological analysis showed healing effect after topical application of natural and organophilizated clay in skin wounds in rats. These analyses favor a good prospect of its application in dermopharmaceuticals, because the use of palygorskite provides greater interaction with skin and heals wounds.
Starting Page	2287
Ending Page	2294
Page Count	8
File Format	PDF
ISSN	13886150
Journal	Journal of thermal analysis
Volume Number	115
Issue Number	3
e-ISSN	15882926
Language	English
Publisher	Springer Netherlands
Publisher Date	2013-01-12
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Palygorskite Organoclay Thermal characterization Histological characterization Potential dermopharmaceuticals Physical Chemistry Analytical Chemistry Polymer Sciences Inorganic Chemistry Measurement Science and Instrumentation
Content Type	Text
Resource Type	Article
Subject	Physical and Theoretical Chemistry Condensed Matter Physics

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