NDLI: Trapping of biological macromolecules in the three-dimensional mesocage pore cavities of monolith adsorbents

Content Provider	Springer Nature Link
Author	Shenashen, M. A. El Safty, Sherif A. Khairy, M.
Copyright Year	2012
Abstract	Gene technology is experiencing remarkable progress, and proteins are becoming crucial in the field of disease diagnosis and treatment. Adsorption of biomolecules on the surface of inorganic materials is an important technique for diagnostic assays and gene applications. In this study, highly ordered mesocage cubic Pm3n aluminumsilica monoliths were fabricated by the one-pot direct-templating of a microemulsion of the liquid crystalline phases of a Brij 56 surfactant. Mesocage cubic Pm3n aluminosilica monoliths with well-defined mesostructures offer high adsorption and loading capacity of proteins from an aqueous solution. Three-dimensional monoliths characterized by spherical pore cavities can potentially perform efficient adsorption and trapping of insulin, cytochrome C, lysozyme, myoglobin, β-lactoglobin proteins. A wide variety of characterization techniques such as SAXS, SEM, TEM, the Brunauer–Emmett–Teller method for nitrogen adsorption and surface area measurements, and TEM were used. The adsorption of proteins as well as the kinetic and thermodynamic characteristics of adsorption was studied, and adsorption isotherms were described by the Langmuir equation. Our findings indicated that monolayer coverage of proteins formed on mesoporous adsorbent surfaces during immobilization and uptake assays. Adsorption efficiency of proteins was attained after a number of reuse cycles, which indicates the presence of mesoporous adsorbents of biomolecules. Integration of mesoporous adsorbents may be feasible in various scientific fields such as nanobioscience, material science, artificial implantation, protein purification, biosensors, drug delivery systems, and molecular biology/biotechnology.
Starting Page	679
Ending Page	692
Page Count	14
File Format	PDF
ISSN	13802224
Journal	Journal of Porous Materials
Volume Number	20
Issue Number	4
e-ISSN	15734854
Language	English
Publisher	Springer US
Publisher Date	2012-10-30
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Protein Mesocage cavities Trapping Three-dimensional aluminosilica Monoliths Adsorption Catalysis Characterization and Evaluation of Materials Physical Chemistry
Content Type	Text
Resource Type	Article
Subject	Mechanics of Materials Materials Science Mechanical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Adsorption of biological macromolecules into mesocage cavities of cubic Pm3n aluminosilica monoliths

Magnetically-separable hierarchically porous carbon monoliths with partially graphitized structures as excellent adsorbents for dyes

Zeolite beta monoliths with hierarchical porosity by the transformation of bimodal pore silica gel

Pore structure control of macroporous methylsilsesquioxane monoliths prepared by in situ two-step processing

Permeability of silica monoliths containing micro- and nano-pores

Syntheses and application of silica monolith with bimodal meso/macroscopic pore structure

Hierarchically porous monoliths of carbon and metal oxides with ordered mesopores

Hydrothermal synthesis of Ni-doped hierarchically porous carbon monoliths for hydrogen storage

CO$_{2}$ adsorption on amine-modified mesoporous silicas

Trapping of biological macromolecules in the three-dimensional mesocage pore cavities of monolith adsorbents

Similar Documents

Adsorption of biological macromolecules into mesocage cavities of cubic Pm3n aluminosilica monoliths

Magnetically-separable hierarchically porous carbon monoliths with partially graphitized structures as excellent adsorbents for dyes

Zeolite beta monoliths with hierarchical porosity by the transformation of bimodal pore silica gel

Pore structure control of macroporous methylsilsesquioxane monoliths prepared by in situ two-step processing

Permeability of silica monoliths containing micro- and nano-pores

Syntheses and application of silica monolith with bimodal meso/macroscopic pore structure

Hierarchically porous monoliths of carbon and metal oxides with ordered mesopores

Hydrothermal synthesis of Ni-doped hierarchically porous carbon monoliths for hydrogen storage

CO$_{2}$ adsorption on amine-modified mesoporous silicas

Trapping of biological macromolecules in the three-dimensional mesocage pore cavities of monolith adsorbents