NDLI: Information Technology-Based Interventions to Improve Drug-Drug Interaction Outcomes: A Systematic Review on Features and Effects

Content Provider	Springer Nature Link
Author	Nabovati, Ehsan Vakili Arki, Hasan Taherzadeh, Zhila Saberi, Mohammad Reza Medlock, Stephanie Abu Hanna, Ameen Eslami, Saeid
Copyright Year	2016
Abstract	The purpose of this systematic review was to identify features and effects of information technology (IT)-based interventions on outcomes related to drug-drug interactions (DDI outcomes). A literature search was conducted in Medline, EMBASE, and the Cochrane Library for published English-language studies. Studies were included if a main outcome was related to DDIs, the intervention involved an IT-based system, and the study design was experimental or observational with controls. Study characteristics, including features and effects of IT-based interventions, were extracted. Nineteen studies comprising five randomized controlled trials (RCT), five non-randomized controlled trials (NRCT) and nine observational studies with controls (OWC) were included. Sixty-four percent of prescriber-directed interventions, and all non-prescriber interventions, were effective. Each of the following characteristics corresponded to groups of studies of which a majority were effective: automatic provision of recommendations within the providers’ workflow, intervention at the time of decision-making, integration into other systems, and requiring the reason for not following the recommendations. Only two studies measured clinical outcomes: an RCT that showed no significant improvement and an OWC that showed improvement, but did not statistically assess the effect. Most studies that measured surrogate outcomes (e.g. potential DDIs) and other outcomes (e.g. adherence to alerts) showed improvements. IT-based interventions improve surrogate clinical outcomes and adherence to DDI alerts. However, there is lack of robust evidence about their effectiveness on clinical outcomes. It is recommended that researchers consider the identified features of effective interventions in the design of interventions and evaluate the effectiveness on DDI outcomes, particularly clinical outcomes.
Starting Page	1
Ending Page	17
Page Count	17
File Format	PDF
ISSN	01485598
Journal	Journal of Medical Systems
Volume Number	41
Issue Number	1
e-ISSN	1573689X
Language	English
Publisher	Springer US
Publisher Date	2016-11-26
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Drug interactions Medication errors Intervention Information technology Decision support systems Systematic review Health Informatics Statistics for Life Sciences, Medicine, Health Sciences
Content Type	Text
Resource Type	Article
Subject	Health Information Management Information Systems Health Informatics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Clinical decision support systems-based interventions to improve medication outcomes: A systematic literature review on features and effects.

Physicians’ Compliance with a Clinical Decision Support System Alerting during the Prescribing Process

Efficiency of Clinical Decision Support Systems Improves with Experience

The Effect of Computerized Physician Order Entry and Decision Support System on Medication Errors in the Neonatal Ward: Experiences from an Iranian Teaching Hospital

How intervention studies measure the effectiveness of medication safety-related clinical decision support systems in primary and long-term care: a systematic review

The effects of clinical decision support system for prescribing medication on patient outcomes and physician practice performance: a systematic review and meta-analysis

Service Oriented Architecture for Clinical Decision Support: A Systematic Review and Future Directions

Introduction: Patient Safety and Medication Errors

A Review of Decision Support Systems in Telecare

Information Technology-Based Interventions to Improve Drug-Drug Interaction Outcomes: A Systematic Review on Features and Effects

Similar Documents

Clinical decision support systems-based interventions to improve medication outcomes: A systematic literature review on features and effects.

Physicians’ Compliance with a Clinical Decision Support System Alerting during the Prescribing Process

Efficiency of Clinical Decision Support Systems Improves with Experience

The Effect of Computerized Physician Order Entry and Decision Support System on Medication Errors in the Neonatal Ward: Experiences from an Iranian Teaching Hospital

How intervention studies measure the effectiveness of medication safety-related clinical decision support systems in primary and long-term care: a systematic review

The effects of clinical decision support system for prescribing medication on patient outcomes and physician practice performance: a systematic review and meta-analysis

Service Oriented Architecture for Clinical Decision Support: A Systematic Review and Future Directions

Introduction: Patient Safety and Medication Errors

A Review of Decision Support Systems in Telecare

Information Technology-Based Interventions to Improve Drug-Drug Interaction Outcomes: A Systematic Review on Features and Effects