NDLI: Apatite-forming PEEK with TiO$_{2}$ surface layer coating

Content Provider	Springer Nature Link
Author	Kizuki, Takashi Matsushita, Tomiharu Kokubo, Tadashi
Copyright Year	2015
Abstract	Polyetheretherketone (PEEK) is widely used in orthopedic implants, such as spinal fusion devices, because of its moderate elastic modulus, as well as relatively high mechanical strength. However, it does not bond to living bone, and hence it needs autograft to be fixed to the bone. In this study, we attempted to add bone-bonding properties to PEEK by coating with TiO$_{2}$ synthesized by the sol–gel process. When a TiO$_{2}$ sol solution consisting of titanium isopropoxide, water, ethanol, and nitric acid was deposited on a PEEK substrate without any pretreatment, the formed TiO$_{2}$ gel layer was easily peeled off after subsequent treatments. However, when the same solution was deposited on PEEK that was preliminarily subjected to UV or O$_{2}$ plasma treatment, the deposited TiO$_{2}$ gel layer strongly adhered to the substrate even after subsequent treatments. The strong adhesion was attributed to the interaction among the C–O, C=O, and O–C=O groups on the PEEK owing to the UV or O$_{2}$ plasma treatment and the Ti–O bond of the TiO$_{2}$ gel. Apatite did not form on the as-formed TiO$_{2}$ gel layer in a simulated body fluid (SBF) even within 3 days; however, apatite formed after soaking in 0.1 M HCl solution at 80 °C for 24 h. This apatite formation was attributed to positive surface charge of the TiO$_{2}$ gel layer induced by the acid treatment. The PEEK with the TiO$_{2}$ gel layer coating formed by the proposed process is expected to bond to living bone, because a positively charged titanium oxide which facilitates the formation of apatite in SBF within a short period is known to bond to living bone.
Starting Page	1
Ending Page	9
Page Count	9
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	26
Issue Number	1
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2015-01-15
Publisher Place	New York
Access Restriction	Subscribed
Subject Keyword	Biomaterials Biomedical Engineering Regenerative Medicine/Tissue Engineering Polymer Sciences Ceramics, Glass, Composites, Natural Methods Surfaces and Interfaces, Thin Films
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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