NDLI: Increased reactivity and in vitro cell response of titanium based implant surfaces after anodic oxidation

Content Provider	Springer Nature Link
Author	Walter, M. S. Frank, M. J. Sunding, M. F. Gómez Florit, M. Monjo, M. Bucko, M. M. Pamula, E. Lyngstadaas, S. P. Haugen, H. J.
Copyright Year	2013
Abstract	In the quest for improved bone growth and attachment around dental implants, chemical surface modifications are one possibility for future developments. The biological properties of titanium based materials can be further enhanced with methods like anodic polarization to produce an active rather than a passive titanium oxide surface. Here we investigate the formation of hydroxide groups on sand blasted and acid etched titanium and titanium–zirconium alloy surfaces after anodic polarization in an alkaline solution. X-ray photoelectron spectroscopy shows that the activated surfaces had increased reactivity. Furthermore the activated surfaces show up to threefold increase in OH$^{−}$ concentration in comparison to the original surface. The surface parameters S$_{a}$, S$_{ku}$, S$_{dr}$ and S$_{sk}$ were more closely correlated to time and current density for titanium than for titanium–zirconium. Studies with MC3T3-E1 osteoblastic cells showed that OH$^{−}$ activated surfaces increased mRNA levels of osteocalcin and collagen-I.
Starting Page	2761
Ending Page	2773
Page Count	13
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	24
Issue Number	12
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2013-08-03
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Biomaterials Polymer Sciences Ceramics, Glass, Composites, Natural Methods Metallic Materials Characterization and Evaluation of Materials Surfaces and Interfaces, Thin Films
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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