NDLI: Application of diverse natural polymers in the design of oral gels for the treatment of periodontal diseases

Content Provider	Springer Nature Link
Author	Ganguly, Auleep Ian, Cheng Kang Sheshala, Ravi Sahu, Priyadarshi Soumyaranjan Al Waeli, Haider Meka, Venkata Srikanth
Copyright Year	2017
Abstract	The objective of this study was to prepare periodontal gels using natural polymers such as badam gum, karaya gum and chitosan. These gels were tested for their physical and biochemical properties and assessed for their antibacterial activity against Aggregatibacter actinomycetemcomitans and Streptococcus mutans, two pathogens associated with periodontal disease. Badam gum, karaya gum and chitosan were used to prepare gels of varying concentrations. Moxifloxacin hydrochloride, a known antimicrobial drug was choosen in the present study and it was added to the above gels. The gels were then run through a battery of tests in order to determine their physical properties such as pH and viscosity. Diffusion studies were carried out on the gels containing the drug. Antimicrobial testing of the gels against various bacteria was then carried out to determine the effectiveness of the gels against these pathogens. The results showed that natural polymers can be used to produce gels. These gels do not have inherent antimicrobial properties against A. actinomycetemcomitans and S. mutans. However, they can be used as a transport vehicle to carry and release antimicrobial drugs.
Starting Page	1
Ending Page	8
Page Count	8
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	28
Issue Number	3
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2017-01-31
Publisher Place	New York
Access Restriction	Subscribed
Subject Keyword	Biomaterials Biomedical Engineering Regenerative Medicine/Tissue Engineering Polymer Sciences Ceramics, Glass, Composites, Natural Materials Surfaces and Interfaces, Thin Films
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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