NDLI: Assessment of in vitro temporal corrosion and cytotoxicity of AZ91D alloy

Content Provider	Springer Nature Link
Author	Del Gaudio, Costanti Bagalà, Paolo Venturini, Marco Grandi, Claudio Parnigotto, Pier Paolo Bianco, Alessandra Montesperelli, Giampiero
Copyright Year	2012
Abstract	Magnesium alloys represent a valuable option for the production of bioresorbable implantable medical devices aimed to improve the therapeutic approach and minimize the potential risks related to biostable materials. In this regard, the degradation process needs to be carefully evaluated in order to assess the effectiveness of the regenerative support and the eventual toxic effects induced by the released corrosion products. Aluminium is one of the most common alloying element that raised several safety concerns, contributing to shift the investigation toward Al-free alloys. To delve into this issue, a long-term investigation (up to 28 days) was performed using AZ91D alloy, due to its relevant Al content. Immersion tests in phosphate buffered saline (PBS) solution was performed following the ASTM standards and the corrosion behaviour was evaluated at fixed time points by means of electrochemical techniques. Cytotoxic effects were assessed by culturing human neuroblastoma cells with conditioned medium derived from immersion tests at different dilution degree. An increase in the resistance corrosion with the time was observed. In all the investigated cases the presence of Al in the conditioned media did not induce significant toxic effects directly correlated to its content. A decrease of cell viability was only observed in the case of 50 % dilution of PBS conditioned for the longest immersion period (i.e., 28 days).
Starting Page	2553
Ending Page	2562
Page Count	10
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	23
Issue Number	10
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2012-07-17
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Polymer Sciences Ceramics, Glass, Composites, Natural Methods Biomaterials Surfaces and Interfaces, Thin Films Characterization and Evaluation of Materials Metallic Materials
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Crystallinity assessment and in vitro cytotoxicity of polylactide scaffolds for biomedical applications

In vitro cytotoxicity of surface modified bismuth nanoparticles

In vitro biocompatibility assessment of PHBV/Wollastonite composites

In vitro biocompatibility and corrosion resistance of a new implant titanium base alloy

Corrosion behaviour of β-Ti20Mo alloy in artificial saliva

Erratum to: Cytotoxicity assessment of modified bioactive glasses with MLO-A5 osteogenic cells in vitro

Cytotoxicity assessment of modified bioactive glasses with MLO-A5 osteogenic cells in vitro

In vitro microhardness of glass ionomer cements

Nanomechanical characterization of tissue engineered bone grown on titanium alloy in vitro

Assessment of in vitro temporal corrosion and cytotoxicity of AZ91D alloy

Similar Documents

Crystallinity assessment and in vitro cytotoxicity of polylactide scaffolds for biomedical applications

In vitro cytotoxicity of surface modified bismuth nanoparticles

In vitro biocompatibility assessment of PHBV/Wollastonite composites

In vitro biocompatibility and corrosion resistance of a new implant titanium base alloy

Corrosion behaviour of β-Ti20Mo alloy in artificial saliva

Erratum to: Cytotoxicity assessment of modified bioactive glasses with MLO-A5 osteogenic cells in vitro

Cytotoxicity assessment of modified bioactive glasses with MLO-A5 osteogenic cells in vitro

In vitro microhardness of glass ionomer cements

Nanomechanical characterization of tissue engineered bone grown on titanium alloy in vitro

Assessment of in vitro temporal corrosion and cytotoxicity of AZ91D alloy