NDLI: Anticorrosion and cytocompatibility behavior of MAO/PLLA modified magnesium alloy WE42

Content Provider	Springer Nature Link
Author	Guo, Meiqing Cao, Lu Lu, Ping Liu, Yin Xu, Xinhua
Copyright Year	2011
Abstract	Recently, biodegradable magnesium alloys have been introduced in the field of cardiovascular stents to avoid the specific drawbacks of permanent metallic implants. However, the major obstacle of the clinical use of magnesium-based materials is their rapid corrosion rate. In this paper, a composite micro-arc oxidation/poly-l-lactic acid (MAO/PLLA) coating was fabricated on the surface of the magnesium alloy WE42 to improve its corrosion resistance and the cytocompatibility of the modified materials was also investigated for safety aim. In our study, the morphology of materials was analyzed by Scanning electron microscopy. Potentiodynamic polarization was used to evaluate the corrosion behavior of the samples and corrosion weight loss was used to demonstrate their degradation rate. Furthermore, we applied cytotoxicity test in testing the cytocompatibility of the modified samples. The results showed that the PLLA coating effectively sealed the microcracks and micropores on the surface of the MAO coating by physical interlocking to interfere the corrosion ions. The corrosion rate was decreased and the cyototoxicity test showed that the MAO/PLLA composite coating WE42 had good cytocompatibility.
Starting Page	1735
Ending Page	1740
Page Count	6
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	22
Issue Number	7
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2011-06-01
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Characterization and Evaluation of Materials Ceramics, Glass, Composites, Natural Methods Surfaces and Interfaces, Thin Films Polymer Sciences Metallic Materials Biomaterials
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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